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This orthogroup contains 168 genes from 109 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 168 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00112 | Peptidase_C1 — Papain family cysteine protease | 135 / 168 | 80.4% | 91.2% of 148 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 143 / 168 | 85.1% | 96.6% of 148 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 135 / 168 | 80.4% | 91.2% of 148 | ≥80% support |
| GO | GO:0008234 Molecular Function | cysteine-type peptidase activity | 135 / 168 | 80.4% | 91.2% of 148 | ≥80% support |
| PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 131 / 168 | 78.0% | 89.1% of 147 | ≥50% support |
| Pfam | PF00031 | Cystatin | 131 / 168 | 78.0% | 88.5% of 148 | ≥50% support |
| Pfam | PF08246 | Inhibitor_I29 — Cathepsin propeptide inhibitor domain (I29) | 126 / 168 | 75.0% | 85.1% of 148 | ≥50% support |
| GO | GO:0004869 Molecular Function | cysteine-type endopeptidase inhibitor activity | 134 / 168 | 79.8% | 90.5% of 148 | ≥50% support |
| GO | GO:0004197 Molecular Function | cysteine-type endopeptidase activity | 131 / 168 | 78.0% | 88.5% of 148 | ≥50% support |
| GO | GO:0005764 Cellular Component | lysosome | 131 / 168 | 78.0% | 88.5% of 148 | ≥50% support |
| GO | GO:0051603 Biological Process | proteolysis involved in protein catabolic process | 131 / 168 | 78.0% | 88.5% of 148 | ≥50% support |
| KEGG | K01373 | CTSF — Peptidases and inhibitors | 105 / 168 | 62.5% | 93.8% of 112 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7383106.1 | KAJ7383106.1 | cysteine-type endopeptidase inhibitor [Desmophyllum pertusum] | E3P6P1 Cystatin OS=Cryptophis nigrescens OX=292442 PE=1 SV=1 | JBrowse |
| Desmophyllum pertusum | KAJ7383107.1 | KAJ7383107.1 | Cathepsin L [Desmophyllum pertusum] | Q26534 Cathepsin L OS=Schistosoma mansoni OX=6183 GN=CL1 PE=2 SV=1 | JBrowse |
