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This orthogroup contains 159 genes from 117 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 159 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR15301 | INSULIN-INDUCED GENE 1 | 145 / 159 | 91.2% | 100.0% of 145 | ≥80% support |
| Pfam | PF07281 | INSIG | 145 / 159 | 91.2% | 100.0% of 145 | ≥80% support |
| GO | GO:0005783 Cellular Component | endoplasmic reticulum | 145 / 159 | 91.2% | 100.0% of 145 | ≥80% support |
| GO | GO:0016126 Biological Process | sterol biosynthetic process | 145 / 159 | 91.2% | 100.0% of 145 | ≥80% support |
| GO | GO:0006695 Biological Process | cholesterol biosynthetic process | 141 / 159 | 88.7% | 97.2% of 145 | ≥80% support |
| GO | GO:0032869 Biological Process | cellular response to insulin stimulus | 141 / 159 | 88.7% | 97.2% of 145 | ≥80% support |
| GO | GO:0032933 Biological Process | SREBP signaling pathway | 141 / 159 | 88.7% | 97.2% of 145 | ≥80% support |
| GO | GO:0032937 Cellular Component | SREBP-SCAP-Insig complex | 141 / 159 | 88.7% | 97.2% of 145 | ≥80% support |
| GO | GO:0036316 Biological Process | SREBP-SCAP complex retention in endoplasmic reticulum | 141 / 159 | 88.7% | 97.2% of 145 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7363143.1 | KAJ7363143.1 | Insulin-induced protein 1 protein [Desmophyllum pertusum] | Q91WG1 Insulin-induced gene 2 protein OS=Mus musculus OX=10090 GN=I | JBrowse |
