Gene Family

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🧬 OG0000249

This orthogroup contains 2,393 genes from 144 species (2,394 sequences — 1 extra sequences share a gene identifier with another member, so they are not counted twice). The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 62.2%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 2,393 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10127DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING1488 / 2,39362.2%68.7%
of 2,166
≥50% support
PfamPF01400Astacin1865 / 2,39377.9%85.8%
of 2,174
≥50% support
PfamPF00090TSP_1 — Thrombospondin type 1 domain1788 / 2,39374.7%82.2%
of 2,174
≥50% support
PfamPF00629MAM1765 / 2,39373.8%81.2%
of 2,174
≥50% support
GOGO:0006508
Biological Process
proteolysis1893 / 2,39379.1%87.6%
of 2,161
≥50% support
GOGO:0004222
Molecular Function
metalloendopeptidase activity1892 / 2,39379.1%87.6%
of 2,161
≥50% support
GOGO:0008237
Molecular Function
metallopeptidase activity1886 / 2,39378.8%87.3%
of 2,161
≥50% support
GOGO:0016020
Cellular Component
membrane1803 / 2,39375.3%83.4%
of 2,161
≥50% support
GOGO:0008270
Molecular Function
zinc ion binding1671 / 2,39369.8%77.3%
of 2,161
≥50% support
📊 Total members in OG0000249: 24 (filtered to ECAVO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Eunicella cavoliniENSLDHP00000000142.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]P98068
Protein SpAN OS=Strongylocentrotus purpuratus OX=7668 GN=SPA
JBrowse
Eunicella cavoliniENSLDHP00000002988.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]Q20191
Zinc metalloproteinase nas-13 OS=Caenorhabditis elegans OX=6
JBrowse
Eunicella cavoliniENSLDHP00000008227.1CAB4013144.1MAM and LDL-receptor class A domain-containing 2-like, partial [Paramuricea clavata]Q96RW7
Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1 PE=1 SV=2
JBrowse
Eunicella cavoliniENSLDHP00000008233.1CAB4013144.1MAM and LDL-receptor class A domain-containing 2-like, partial [Paramuricea clavata]Q96RW7
Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1 PE=1 SV=2
JBrowse
Eunicella cavoliniENSLDHP00000015613.1CAB4013143.1astacin-like metalloendopeptidase, partial [Paramuricea clavata]Q16820
Meprin A subunit beta OS=Homo sapiens OX=9606 GN=MEP1B PE=1
JBrowse
Eunicella cavoliniENSLDHP00000015624.1CAB4013143.1astacin-like metalloendopeptidase, partial [Paramuricea clavata]B3EWZ6
MAM and LDL-receptor class A domain-containing protein 2 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000016643.1XP_028405803.1uncharacterized protein LOC114528384 [Dendronephthya gigantea]B3EWZ6
MAM and LDL-receptor class A domain-containing protein 2 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000020972.1XP_028405804.1zinc metalloproteinase nas-30-like [Dendronephthya gigantea]Q9U3S9
Zinc metalloproteinase nas-6 OS=Caenorhabditis elegans OX=62
JBrowse
Eunicella cavoliniENSLDHP00000021219.1CAB3990650.1Zinc metallo ase nas-15 [Paramuricea clavata]Q20191
Zinc metalloproteinase nas-13 OS=Caenorhabditis elegans OX=6
JBrowse
Eunicella cavoliniENSLDHP00000025209.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]B3EWZ3
Coadhesin (Fragment) OS=Acropora millepora OX=45264 PE=1 SV=
JBrowse
Eunicella cavoliniENSLDHP00000038585.1CAB3999791.1MAM and LDL-receptor class A domain-containing 2-like [Paramuricea clavata]B3EWZ6
MAM and LDL-receptor class A domain-containing protein 2 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000038962.1CAB3992768.1MAM and LDL-receptor class A domain-containing 1-like [Paramuricea clavata]B3EWZ5
MAM and LDL-receptor class A domain-containing protein 1 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000038972.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]B3EWZ5
MAM and LDL-receptor class A domain-containing protein 1 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000039555.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]P07996
Thrombospondin-1 OS=Homo sapiens OX=9606 GN=THBS1 PE=1 SV=2
JBrowse
Eunicella cavoliniENSLDHP00000039885.1CAB3992768.1MAM and LDL-receptor class A domain-containing 1-like [Paramuricea clavata]B3EWZ5
MAM and LDL-receptor class A domain-containing protein 1 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000040095.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]Q20191
Zinc metalloproteinase nas-13 OS=Caenorhabditis elegans OX=6
JBrowse
Eunicella cavoliniENSLDHP00000040112.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]Q20191
Zinc metalloproteinase nas-13 OS=Caenorhabditis elegans OX=6
JBrowse
Eunicella cavoliniENSLDHP00000040341.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]B3EWZ6
MAM and LDL-receptor class A domain-containing protein 2 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000040351.1CAB4008039.1Meprin A subunit beta, partial [Paramuricea clavata]B3EWZ6
MAM and LDL-receptor class A domain-containing protein 2 (Fr
JBrowse
Eunicella cavoliniENSLDHP00000042338.1CAB3999791.1MAM and LDL-receptor class A domain-containing 2-like [Paramuricea clavata]B3EWZ6
MAM and LDL-receptor class A domain-containing protein 2 (Fr
JBrowse
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