← Back to the gene family browser
This orthogroup contains 1,378 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,378 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11412 | MACROGLOBULIN / COMPLEMENT | 1180 / 1,378 | 85.6% | 99.8% of 1,182 | ≥80% support |
| Pfam | PF07678 | TED_complement — A-macroglobulin TED domain | 776 / 1,378 | 56.3% | 66.0% of 1,175 | ≥50% support |
| Pfam | PF07703 | A2M_BRD — Alpha-2-macroglobulin bait region domain | 728 / 1,378 | 52.8% | 62.0% of 1,175 | ≥50% support |
| Pfam | PF00207 | A2M — Alpha-2-macroglobulin family | 707 / 1,378 | 51.3% | 60.2% of 1,175 | ≥50% support |
| GO | GO:0004866 Molecular Function | endopeptidase inhibitor activity | 869 / 1,378 | 63.1% | 83.4% of 1,042 | ≥50% support |
| GO | GO:0005615 Cellular Component | extracellular space | 776 / 1,378 | 56.3% | 74.5% of 1,042 | ≥50% support |
| GO | GO:0005576 Cellular Component | extracellular region | 698 / 1,378 | 50.7% | 67.0% of 1,042 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000011281.1 | XP_028411915.1 | CD109 antigen-like isoform X1 [Dendronephthya gigantea] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000013556.1 | XP_028411915.1 | CD109 antigen-like isoform X1 [Dendronephthya gigantea] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000013577.1 | XP_028411915.1 | CD109 antigen-like isoform X1 [Dendronephthya gigantea] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000013588.1 | XP_028411915.1 | CD109 antigen-like isoform X1 [Dendronephthya gigantea] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000026289.1 | CAB4033924.1 | pregnancy zone, partial [Paramuricea clavata] | P28665 Murinoglobulin-1 OS=Mus musculus OX=10090 GN=Mug1 PE=1 SV=3 | JBrowse |
| Eunicella cavolini | ENSLDHP00000026702.1 | CAB3978842.1 | alpha-2-macroglobulin-like isoform X1, partial [Paramuricea clavata] | A8K2U0 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 | JBrowse |
| Eunicella cavolini | ENSLDHP00000027580.1 | CAB3978842.1 | alpha-2-macroglobulin-like isoform X1, partial [Paramuricea clavata] | A8K2U0 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 | JBrowse |
| Eunicella cavolini | ENSLDHP00000027586.1 | CAB4021533.1 | alpha-2-macroglobulin-like isoform X2, partial [Paramuricea clavata] | Q6YHK3 CD109 antigen OS=Homo sapiens OX=9606 GN=CD109 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000027598.1 | CAB3980132.1 | C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata] | Q8IZJ3 C3 and PZP-like alpha-2-macroglobulin domain-containing prot | JBrowse |
| Eunicella cavolini | ENSLDHP00000027616.1 | XP_028400032.1 | murinoglobulin-1-like isoform X1 [Dendronephthya gigantea] | P01023 Alpha-2-macroglobulin OS=Homo sapiens OX=9606 GN=A2M PE=1 SV | JBrowse |
| Eunicella cavolini | ENSLDHP00000027631.1 | CAB3980132.1 | C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata] | Q8IZJ3 C3 and PZP-like alpha-2-macroglobulin domain-containing prot | JBrowse |
| Eunicella cavolini | ENSLDHP00000027635.1 | CAB3996503.1 | C3 and PZP-like alpha-2-macroglobulin domain-containing 8 isoform X1, partial [Paramuricea clavata] | Q8IZJ3 C3 and PZP-like alpha-2-macroglobulin domain-containing prot | JBrowse |
| Eunicella cavolini | ENSLDHP00000027870.1 | CAB4010718.1 | alpha-2-macroglobulin-like isoform X2, partial [Paramuricea clavata] | Q5R4N8 Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV | JBrowse |
| Eunicella cavolini | ENSLDHP00000027943.1 | CAB3996503.1 | C3 and PZP-like alpha-2-macroglobulin domain-containing 8 isoform X1, partial [Paramuricea clavata] | P14046 Alpha-1-inhibitor 3 OS=Rattus norvegicus OX=10116 GN=A1i3 PE | JBrowse |
| Eunicella cavolini | ENSLDHP00000027949.1 | CAB4022459.1 | Hypothetical predicted protein, partial [Paramuricea clavata] | P06684 Complement C5 OS=Mus musculus OX=10090 GN=C5 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000027960.1 | CAB3996504.1 | pregnancy zone -like, partial [Paramuricea clavata] | P28665 Murinoglobulin-1 OS=Mus musculus OX=10090 GN=Mug1 PE=1 SV=3 | JBrowse |
| Eunicella cavolini | ENSLDHP00000028442.1 | CAB3978842.1 | alpha-2-macroglobulin-like isoform X1, partial [Paramuricea clavata] | – | JBrowse |
| Eunicella cavolini | ENSLDHP00000028449.1 | CAB3986701.1 | pregnancy zone -like, partial [Paramuricea clavata] | A8K2U0 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 | JBrowse |
| Eunicella cavolini | ENSLDHP00000028458.1 | CAB3978842.1 | alpha-2-macroglobulin-like isoform X1, partial [Paramuricea clavata] | A8K2U0 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 | JBrowse |
| Eunicella cavolini | ENSLDHP00000028505.1 | CAB4010718.1 | alpha-2-macroglobulin-like isoform X2, partial [Paramuricea clavata] | Q5R4N8 Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV | JBrowse |
