Gene Family

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Member genes
1,378
Species
143
Sequences
1,378
Best annotation support
85.6%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 85.6% of the 1,378 members.

Support counts the member genes carrying the term. % of genes is that count over all 1,378 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11412MACROGLOBULIN / COMPLEMENT1180 / 1,37885.6%99.8%
of 1,182
≥80% support
PfamPF07678TED_complement — A-macroglobulin TED domain776 / 1,37856.3%66.0%
of 1,175
≥50% support
PfamPF07703A2M_BRD — Alpha-2-macroglobulin bait region domain728 / 1,37852.8%62.0%
of 1,175
≥50% support
PfamPF00207A2M — Alpha-2-macroglobulin family707 / 1,37851.3%60.2%
of 1,175
≥50% support
GOGO:0004866
Molecular Function
endopeptidase inhibitor activity869 / 1,37863.1%83.4%
of 1,042
≥50% support
GOGO:0005615
Cellular Component
extracellular space776 / 1,37856.3%74.5%
of 1,042
≥50% support
GOGO:0005576
Cellular Component
extracellular region698 / 1,37850.7%67.0%
of 1,042
≥50% support
📊 Total members in OG0000509: 46 (filtered to ECAVO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Eunicella cavoliniENSLDHP00000028508.1CAB4010718.1alpha-2-macroglobulin-like isoform X2, partial [Paramuricea clavata]Q5R4N8
Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV
JBrowse
Eunicella cavoliniENSLDHP00000028596.1CAB3998482.1Hypothetical predicted protein [Paramuricea clavata]JBrowse
Eunicella cavoliniENSLDHP00000028603.1CAB4015848.1Hypothetical predicted protein [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000028613.1CAB4022459.1Hypothetical predicted protein, partial [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000028621.1CAB3980132.1C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000028801.1CAB4022459.1Hypothetical predicted protein, partial [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000028819.1XP_028400034.1murinoglobulin-1-like isoform X3 [Dendronephthya gigantea]A8K2U0
Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606
JBrowse
Eunicella cavoliniENSLDHP00000028856.1CAB4010718.1alpha-2-macroglobulin-like isoform X2, partial [Paramuricea clavata]P28665
Murinoglobulin-1 OS=Mus musculus OX=10090 GN=Mug1 PE=1 SV=3
JBrowse
Eunicella cavoliniENSLDHP00000028867.1XP_028400036.1pregnancy zone protein-like isoform X5 [Dendronephthya gigantea]Q5R4N8
Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV
JBrowse
Eunicella cavoliniENSLDHP00000028880.1CAB3978842.1alpha-2-macroglobulin-like isoform X1, partial [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000028889.1CAB4017955.1alpha-2-macroglobulin-like isoform X1 [Paramuricea clavata]P20742
Pregnancy zone protein OS=Homo sapiens OX=9606 GN=PZP PE=1 S
JBrowse
Eunicella cavoliniENSLDHP00000028902.1XP_028416699.1pregnancy zone protein-like [Dendronephthya gigantea]P06238
Alpha-2-macroglobulin OS=Rattus norvegicus OX=10116 GN=A2m P
JBrowse
Eunicella cavoliniENSLDHP00000029073.1XP_028416699.1pregnancy zone protein-like [Dendronephthya gigantea]Q5R4N8
Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV
JBrowse
Eunicella cavoliniENSLDHP00000029089.1XP_028400032.1murinoglobulin-1-like isoform X1 [Dendronephthya gigantea]Q5R4N8
Alpha-2-macroglobulin OS=Pongo abelii OX=9601 GN=A2M PE=2 SV
JBrowse
Eunicella cavoliniENSLDHP00000029423.1CAB3980132.1C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata]P28665
Murinoglobulin-1 OS=Mus musculus OX=10090 GN=Mug1 PE=1 SV=3
JBrowse
Eunicella cavoliniENSLDHP00000029445.1CAB3980132.1C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000030719.1CAB3980132.1C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata]JBrowse
Eunicella cavoliniENSLDHP00000031073.1CAB3980132.1C3 and PZP-like alpha-2-macroglobulin domain-containing 8 [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000032512.1CAB4022459.1Hypothetical predicted protein, partial [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
Eunicella cavoliniENSLDHP00000036588.1CAB3988759.1C3 and PZP-like alpha-2-macroglobulin domain-containing 8 isoform X2, partial [Paramuricea clavata]Q8IZJ3
C3 and PZP-like alpha-2-macroglobulin domain-containing prot
JBrowse
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