Gene Family

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Member genes
1,236
Species
148
Sequences
1,236
Best annotation support
80.3%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 80.3% of the 1,236 members.

Support counts the member genes carrying the term. % of genes is that count over all 1,236 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10869PROLYL 4-HYDROXYLASE ALPHA SUBUNIT992 / 1,23680.3%99.2%
of 1,000
≥80% support
GOGO:0004656
Molecular Function
procollagen-proline 4-dioxygenase activity1089 / 1,23688.1%98.6%
of 1,104
≥80% support
GOGO:0005783
Cellular Component
endoplasmic reticulum1089 / 1,23688.1%98.6%
of 1,104
≥80% support
GOGO:0005515
Molecular Function
protein binding1000 / 1,23680.9%90.6%
of 1,104
≥80% support
GOGO:0018401
Biological Process
peptidyl-proline hydroxylation to 4-hydroxy-L-proline992 / 1,23680.3%89.9%
of 1,104
≥80% support
PfamPF08336P4Ha_N — Prolyl 4-Hydroxylase alpha-subunit, N-terminal region955 / 1,23677.3%89.3%
of 1,069
≥50% support
PfamPF136402OG-FeII_Oxy_3 — 2OG-Fe(II) oxygenase superfamily888 / 1,23671.8%83.1%
of 1,069
≥50% support
GOGO:0005506
Molecular Function
iron ion binding953 / 1,23677.1%86.3%
of 1,104
≥50% support
GOGO:0016705
Molecular Function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen952 / 1,23677.0%86.2%
of 1,104
≥50% support
GOGO:0031418
Molecular Function
L-ascorbic acid binding952 / 1,23677.0%86.2%
of 1,104
≥50% support
KEGGK00472P4HA — Arginine and proline metabolism899 / 1,23672.7%99.0%
of 908
≥50% support
📊 Total members in OG0000561: 12 (filtered to ECAVO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Eunicella cavoliniENSLDHP00000017695.1XP_028405013.1prolyl 4-hydroxylase subunit alpha-1-like [Dendronephthya gigantea]Q60715
Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=1009
JBrowse
Eunicella cavoliniENSLDHP00000017733.1XP_028405013.1prolyl 4-hydroxylase subunit alpha-1-like [Dendronephthya gigantea]Q60715
Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=1009
JBrowse
Eunicella cavoliniENSLDHP00000018765.1CAB3985216.1prolyl 4-hydroxylase subunit alpha-1-like [Paramuricea clavata]P54001
Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus OX
JBrowse
Eunicella cavoliniENSLDHP00000018771.1CAB3985216.1prolyl 4-hydroxylase subunit alpha-1-like [Paramuricea clavata]P54001
Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus OX
JBrowse
Eunicella cavoliniENSLDHP00000018785.1CAB3985216.1prolyl 4-hydroxylase subunit alpha-1-like [Paramuricea clavata]Q60715
Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=1009
JBrowse
Eunicella cavoliniENSLDHP00000018794.1CAB3985217.1prolyl 4-hydroxylase subunit alpha-1-like [Paramuricea clavata]Q60715
Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=1009
JBrowse
Eunicella cavoliniENSLDHP00000018810.1CAB3985216.1prolyl 4-hydroxylase subunit alpha-1-like [Paramuricea clavata]P54001
Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus OX
JBrowse
Eunicella cavoliniENSLDHP00000038619.1CAB3982434.1prolyl 4-hydroxylase subunit alpha-1 isoform X1 [Paramuricea clavata]O15460
Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606
JBrowse
Eunicella cavoliniENSLDHP00000038631.1CAB3982434.1prolyl 4-hydroxylase subunit alpha-1 isoform X1 [Paramuricea clavata]Q5ZLK5
Prolyl 4-hydroxylase subunit alpha-2 OS=Gallus gallus OX=903
JBrowse
Eunicella cavoliniENSLDHP00000038639.1CAB3982434.1prolyl 4-hydroxylase subunit alpha-1 isoform X1 [Paramuricea clavata]O15460
Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606
JBrowse
Eunicella cavoliniENSLDHP00000047078.1CAB3992500.1Prolyl 4-hydroxylase subunit alpha-2 [Paramuricea clavata]Q20065
Prolyl 4-hydroxylase subunit alpha-2 OS=Caenorhabditis elega
JBrowse
Eunicella cavoliniENSLDHP00000047089.1XP_028418603.1prolyl 4-hydroxylase subunit alpha-1-like isoform X3 [Dendronephthya gigantea]P54001
Prolyl 4-hydroxylase subunit alpha-1 OS=Rattus norvegicus OX
JBrowse
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