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This orthogroup contains 924 genes from 108 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 924 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13954 | IRE1-RELATED | 498 / 924 | 53.9% | 59.2% of 841 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 728 / 924 | 78.8% | 86.7% of 840 | ≥50% support |
| Pfam | PF06479 | Ribonuc_2-5A — Ribonuclease 2-5A | 618 / 924 | 66.9% | 73.6% of 840 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 739 / 924 | 80.0% | 86.7% of 852 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 739 / 924 | 80.0% | 86.7% of 852 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 739 / 924 | 80.0% | 86.7% of 852 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 648 / 924 | 70.1% | 76.1% of 852 | ≥50% support |
| GO | GO:0004540 Molecular Function | RNA nuclease activity | 623 / 924 | 67.4% | 73.1% of 852 | ≥50% support |
| GO | GO:0006397 Biological Process | mRNA processing | 621 / 924 | 67.2% | 72.9% of 852 | ≥50% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 507 / 924 | 54.9% | 59.5% of 852 | ≥50% support |
| GO | GO:0004521 Molecular Function | RNA endonuclease activity | 498 / 924 | 53.9% | 58.5% of 852 | ≥50% support |
| GO | GO:0030968 Biological Process | endoplasmic reticulum unfolded protein response | 498 / 924 | 53.9% | 58.5% of 852 | ≥50% support |
| GO | GO:0036498 Biological Process | IRE1-mediated unfolded protein response | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
| GO | GO:0051082 Molecular Function | unfolded protein binding | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
| GO | GO:0070059 Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
| GO | GO:1990604 Cellular Component | IRE1-TRAF2-ASK1 complex | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000001303.1 | XP_028408413.1 | uncharacterized protein LOC114530986 [Dendronephthya gigantea] | Q556Q3 Probable serine/threonine-protein kinase irlF OS=Dictyosteli | JBrowse |
| Eunicella cavolini | ENSLDHP00000010395.1 | CAB4042838.1 | Serine threonine- kinase endoribonuclease ire-1, partial [Paramuricea clavata] | – | JBrowse |
| Eunicella cavolini | ENSLDHP00000011461.1 | CAB4040121.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | Q55DJ8 Probable serine/threonine-protein kinase irlC OS=Dictyosteli | JBrowse |
| Eunicella cavolini | ENSLDHP00000011468.1 | CAB4040121.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | Q557G1 Probable serine/threonine-protein kinase irlB OS=Dictyosteli | JBrowse |
| Eunicella cavolini | ENSLDHP00000011476.1 | CAB4040121.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | G0RBE3 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Hyp | JBrowse |
| Eunicella cavolini | ENSLDHP00000011480.1 | CAB4040121.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | – | JBrowse |
| Eunicella cavolini | ENSLDHP00000011604.1 | XP_028392371.1 | uncharacterized protein LOC114516947 [Dendronephthya gigantea] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Eunicella cavolini | ENSLDHP00000011610.1 | XP_028392371.1 | uncharacterized protein LOC114516947 [Dendronephthya gigantea] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Eunicella cavolini | ENSLDHP00000012598.1 | XP_028392371.1 | uncharacterized protein LOC114516947 [Dendronephthya gigantea] | Q557G1 Probable serine/threonine-protein kinase irlB OS=Dictyosteli | JBrowse |
| Eunicella cavolini | ENSLDHP00000013963.1 | CAB4040121.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | Q557G1 Probable serine/threonine-protein kinase irlB OS=Dictyosteli | JBrowse |
| Eunicella cavolini | ENSLDHP00000015158.1 | CAB4040121.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | Q557G1 Probable serine/threonine-protein kinase irlB OS=Dictyosteli | JBrowse |
| Eunicella cavolini | ENSLDHP00000020407.1 | XP_028408413.1 | uncharacterized protein LOC114530986 [Dendronephthya gigantea] | Q09499 Serine/threonine-protein kinase/endoribonuclease ire-1 OS=Ca | JBrowse |
| Eunicella cavolini | ENSLDHP00000022095.1 | XP_028408413.1 | uncharacterized protein LOC114530986 [Dendronephthya gigantea] | O94537 Sensor for unfolded proteins in the ER ire1 OS=Schizosacchar | JBrowse |
| Eunicella cavolini | ENSLDHP00000029389.1 | CAB3999420.1 | serine threonine- kinase endoribonuclease IRE1-like [Paramuricea clavata] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Eunicella cavolini | ENSLDHP00000029394.1 | CAB4033822.1 | serine threonine- kinase endoribonuclease IRE1-like, partial [Paramuricea clavata] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Eunicella cavolini | ENSLDHP00000032502.1 | CAB4023512.1 | ankyrin repeat [Paramuricea clavata] | – | JBrowse |
| Eunicella cavolini | ENSLDHP00000038048.1 | CAB4021650.1 | serine threonine- kinase endoribonuclease IRE1-like [Paramuricea clavata] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Eunicella cavolini | ENSLDHP00000039996.1 | CAB3999418.1 | probable myosin light chain kinase DDB_G0292624 [Paramuricea clavata] | Q7XIT1 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Ory | JBrowse |
