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This orthogroup contains 717 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 717 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF03045 | DAN | 622 / 717 | 86.8% | 100.0% of 622 | ≥80% support |
| PANTHER | PTHR15283 | GREMLIN 1 | 463 / 717 | 64.6% | 81.7% of 567 | ≥50% support |
| GO | GO:0005615 Cellular Component | extracellular space | 463 / 717 | 64.6% | 99.6% of 465 | ≥50% support |
| GO | GO:0009887 Biological Process | animal organ morphogenesis | 463 / 717 | 64.6% | 99.6% of 465 | ≥50% support |
| GO | GO:0036122 Molecular Function | BMP binding | 463 / 717 | 64.6% | 99.6% of 465 | ≥50% support |
| GO | GO:0038098 Biological Process | sequestering of BMP from receptor via BMP binding | 463 / 717 | 64.6% | 99.6% of 465 | ≥50% support |
| GO | GO:0048018 Molecular Function | receptor ligand activity | 463 / 717 | 64.6% | 99.6% of 465 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000012676.1 | XP_028410869.1 | gremlin-2-like [Dendronephthya gigantea] | O73754 Gremlin-1 OS=Xenopus laevis OX=8355 GN=grem1 PE=2 SV=1 | JBrowse |
| Eunicella cavolini | ENSLDHP00000012685.1 | XP_028410869.1 | gremlin-2-like [Dendronephthya gigantea] | O73754 Gremlin-1 OS=Xenopus laevis OX=8355 GN=grem1 PE=2 SV=1 | JBrowse |
| Eunicella cavolini | ENSLDHP00000043306.1 | CAB3984695.1 | gremlin-2 isoform X2 [Paramuricea clavata] | O88273 Gremlin-2 OS=Mus musculus OX=10090 GN=Grem2 PE=1 SV=1 | JBrowse |
| Eunicella cavolini | ENSLDHP00000043635.1 | CAB3981715.1 | neuroblastoma suppressor of tumorigenicity 1 [Paramuricea clavata] | Q90YC9 Neuroblastoma suppressor of tumorigenicity 1 OS=Gallus gallu | JBrowse |