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This orthogroup contains 573 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 573 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0004176 Molecular Function | ATP-dependent peptidase activity | 518 / 573 | 90.4% | 99.6% of 520 | ≥80% support |
| GO | GO:0004252 Molecular Function | serine-type endopeptidase activity | 518 / 573 | 90.4% | 99.6% of 520 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 516 / 573 | 90.1% | 99.2% of 520 | ≥80% support |
| GO | GO:0030163 Biological Process | protein catabolic process | 516 / 573 | 90.1% | 99.2% of 520 | ≥80% support |
| Pfam | PF05362 | Lon_C — Lon protease (S16) C-terminal proteolytic domain | 452 / 573 | 78.9% | 87.1% of 519 | ≥50% support |
| Pfam | PF00004 | AAA | 424 / 573 | 74.0% | 81.7% of 519 | ≥50% support |
| Pfam | PF02190 | LON_substr_bdg — ATP-dependent protease La (LON) substrate-binding domain | 400 / 573 | 69.8% | 77.1% of 519 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 455 / 573 | 79.4% | 87.5% of 520 | ≥50% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 424 / 573 | 74.0% | 81.5% of 520 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000038919.1 | XP_046838988.1 | lon protease homolog, mitochondrial-like [Xenia sp. Carnegie-2017] | P36776 Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 | JBrowse |
| Eunicella cavolini | ENSLDHP00000038931.1 | XP_028411313.1 | lon protease homolog, mitochondrial-like [Dendronephthya gigantea] | Q924S5 Lon protease homolog, mitochondrial OS=Rattus norvegicus OX= | JBrowse |
