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This orthogroup contains 408 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 408 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46345 | INVERTED FORMIN-2 | 327 / 408 | 80.2% | 99.4% of 329 | ≥80% support |
| Pfam | PF02181 | FH2 — Formin Homology 2 Domain | 305 / 408 | 74.8% | 93.0% of 328 | ≥50% support |
| Pfam | PF06367 | Drf_FH3 — Diaphanous FH3 Domain | 294 / 408 | 72.1% | 89.6% of 328 | ≥50% support |
| Pfam | PF06371 | Drf_GBD — Diaphanous GTPase-binding Domain | 259 / 408 | 63.5% | 79.0% of 328 | ≥50% support |
| GO | GO:0003779 Molecular Function | actin binding | 295 / 408 | 72.3% | 98.7% of 299 | ≥50% support |
| GO | GO:0016043 Biological Process | cellular component organization | 294 / 408 | 72.1% | 98.3% of 299 | ≥50% support |
| GO | GO:0030036 Biological Process | actin cytoskeleton organization | 263 / 408 | 64.5% | 88.0% of 299 | ≥50% support |
| GO | GO:0031267 Molecular Function | small GTPase binding | 263 / 408 | 64.5% | 88.0% of 299 | ≥50% support |
| KEGG | K23958 | INF2 — Cytoskeleton proteins | 245 / 408 | 60.1% | 96.5% of 254 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000035522.1 | CAB4005147.1 | Inverted formin-2 [Paramuricea clavata] | Q0IHV1 Inverted formin-2 OS=Xenopus tropicalis OX=8364 GN=inf2 PE=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000035531.1 | CAB4005146.1 | inverted formin-2 isoform X1 [Paramuricea clavata] | Q27J81 Inverted formin-2 OS=Homo sapiens OX=9606 GN=INF2 PE=1 SV=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000036779.1 | CAB4012630.1 | inverted formin-2-like isoform X1 [Paramuricea clavata] | Q0IHV1 Inverted formin-2 OS=Xenopus tropicalis OX=8364 GN=inf2 PE=2 | JBrowse |
| Eunicella cavolini | ENSLDHP00000036790.1 | CAB4012630.1 | inverted formin-2-like isoform X1 [Paramuricea clavata] | Q0IHV1 Inverted formin-2 OS=Xenopus tropicalis OX=8364 GN=inf2 PE=2 | JBrowse |
