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This orthogroup contains 283 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 283 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0006886 Biological Process | intracellular protein transport | 242 / 283 | 85.5% | 99.6% of 243 | ≥80% support |
| GO | GO:0016192 Biological Process | vesicle-mediated transport | 242 / 283 | 85.5% | 99.6% of 243 | ≥80% support |
| GO | GO:0030117 Cellular Component | membrane coat | 241 / 283 | 85.2% | 99.2% of 243 | ≥80% support |
| PANTHER | PTHR22780 | ADAPTIN, ALPHA/GAMMA/EPSILON | 209 / 283 | 73.9% | 99.5% of 210 | ≥50% support |
| Pfam | PF01602 | Adaptin_N — Adaptin N terminal region | 207 / 283 | 73.1% | 85.5% of 242 | ≥50% support |
| Pfam | PF02296 | Alpha_adaptin_C — Alpha adaptin AP2, C-terminal domain | 174 / 283 | 61.5% | 71.9% of 242 | ≥50% support |
| Pfam | PF02883 | Alpha_adaptinC2 — Adaptin C-terminal domain | 153 / 283 | 54.1% | 63.2% of 242 | ≥50% support |
| GO | GO:0140312 Molecular Function | cargo adaptor activity | 209 / 283 | 73.9% | 86.0% of 243 | ≥50% support |
| GO | GO:0030122 Cellular Component | AP-2 adaptor complex | 208 / 283 | 73.5% | 85.6% of 243 | ≥50% support |
| GO | GO:0035615 Molecular Function | clathrin adaptor activity | 208 / 283 | 73.5% | 85.6% of 243 | ≥50% support |
| GO | GO:0072583 Biological Process | clathrin-dependent endocytosis | 208 / 283 | 73.5% | 85.6% of 243 | ≥50% support |
| GO | GO:0030131 Cellular Component | clathrin adaptor complex | 174 / 283 | 61.5% | 71.6% of 243 | ≥50% support |
| KEGG | K11824 | AP2A — Exosome | 148 / 283 | 52.3% | 97.4% of 152 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000003464.1 | CAB4005368.1 | AP-2 complex subunit alpha-2 isoform X2 [Paramuricea clavata] | O95782 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A | JBrowse |
| Eunicella cavolini | ENSLDHP00000003473.1 | CAB4005368.1 | AP-2 complex subunit alpha-2 isoform X2 [Paramuricea clavata] | O95782 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A | JBrowse |
| Eunicella cavolini | ENSLDHP00000003499.1 | XP_028403920.1 | AP-2 complex subunit alpha-2-like [Dendronephthya gigantea] | P18484 AP-2 complex subunit alpha-2 OS=Rattus norvegicus OX=10116 G | JBrowse |
| Eunicella cavolini | ENSLDHP00000003519.1 | XP_028403920.1 | AP-2 complex subunit alpha-2-like [Dendronephthya gigantea] | P18484 AP-2 complex subunit alpha-2 OS=Rattus norvegicus OX=10116 G | JBrowse |
| Eunicella cavolini | ENSLDHP00000003529.1 | XP_028403920.1 | AP-2 complex subunit alpha-2-like [Dendronephthya gigantea] | P18484 AP-2 complex subunit alpha-2 OS=Rattus norvegicus OX=10116 G | JBrowse |
