Gene Family

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Member genes
258
Species
138
Sequences
258
Best annotation support
81.8%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 81.8% of the 258 members.

Support counts the member genes carrying the term. % of genes is that count over all 258 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00018SH3_1 — SH3 domain211 / 25881.8%96.8%
of 218
≥80% support
GOGO:0005515
Molecular Function
protein binding216 / 25883.7%98.6%
of 219
≥80% support
PANTHERPTHR19969SH2-SH3 ADAPTOR PROTEIN-RELATED205 / 25879.5%95.8%
of 214
≥50% support
PfamPF00017SH2201 / 25877.9%92.2%
of 218
≥50% support
PfamPF07653SH3_2 — Variant SH3 domain199 / 25877.1%91.3%
of 218
≥50% support
GOGO:0007165
Biological Process
signal transduction205 / 25879.5%93.6%
of 219
≥50% support
GOGO:0016477
Biological Process
cell migration205 / 25879.5%93.6%
of 219
≥50% support
GOGO:0030971
Molecular Function
receptor tyrosine kinase binding205 / 25879.5%93.6%
of 219
≥50% support
GOGO:0035591
Molecular Function
signaling adaptor activity205 / 25879.5%93.6%
of 219
≥50% support
KEGGK04438CRK, CRKII — Bacterial invasion of epithelial cells174 / 25867.4%100.0%
of 174
≥50% support
📊 Total members in OG0004424: 2 (filtered to ECAVO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Eunicella cavoliniENSLDHP00000017621.1XP_028393558.1adapter molecule crk-like [Dendronephthya gigantea]P87378
Adapter molecule crk OS=Xenopus laevis OX=8355 GN=crk PE=2 S
JBrowse
Eunicella cavoliniENSLDHP00000017632.1XP_028393558.1adapter molecule crk-like [Dendronephthya gigantea]P87378
Adapter molecule crk OS=Xenopus laevis OX=8355 GN=crk PE=2 S
JBrowse
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