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This orthogroup contains 251 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 251 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR31120 | METALLOPROTEASE TIKI | 231 / 251 | 92.0% | 99.6% of 232 | ≥80% support |
| Pfam | PF01963 | TraB_PrgY_gumN — TraB/PrgY/gumN family | 229 / 251 | 91.2% | 99.6% of 230 | ≥80% support |
| GO | GO:0004175 Molecular Function | endopeptidase activity | 231 / 251 | 92.0% | 99.6% of 232 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 231 / 251 | 92.0% | 99.6% of 232 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 231 / 251 | 92.0% | 99.6% of 232 | ≥80% support |
| GO | GO:0030178 Biological Process | negative regulation of Wnt signaling pathway | 231 / 251 | 92.0% | 99.6% of 232 | ≥80% support |
| KEGG | K25185 | TRABD2 — Peptidases and inhibitors | 154 / 251 | 61.4% | 100.0% of 154 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Eunicella cavolini | ENSLDHP00000027931.1 | CAB4025035.1 | Metalloprotease TIKI2, partial, partial [Paramuricea clavata] | A7RX69 Metalloprotease TIKI homolog OS=Nematostella vectensis OX=45 | JBrowse |
| Eunicella cavolini | ENSLDHP00000027940.1 | XP_028401249.1 | metalloprotease TIKI homolog isoform X2 [Dendronephthya gigantea] | P0DJQ9 Metalloprotease TIKI2 OS=Xenopus tropicalis OX=8364 GN=trabd | JBrowse |
| Eunicella cavolini | ENSLDHP00000029379.1 | CAB3991173.1 | Hypothetical predicted protein [Paramuricea clavata] | A7RX69 Metalloprotease TIKI homolog OS=Nematostella vectensis OX=45 | JBrowse |
| Eunicella cavolini | ENSLDHP00000029558.1 | CAB3990706.1 | metalloprotease TIKI1 [Paramuricea clavata] | F6PTN1 Metalloprotease TIKI1 OS=Xenopus tropicalis OX=8364 GN=trabd | JBrowse |
| Eunicella cavolini | ENSLDHP00000029566.1 | CAB3990705.1 | metalloprotease TIKI1 [Paramuricea clavata] | P0DJQ9 Metalloprotease TIKI2 OS=Xenopus tropicalis OX=8364 GN=trabd | JBrowse |
