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This orthogroup contains 304 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 304 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23076 | METALLOPROTEASE M41 FTSH | 269 / 304 | 88.5% | 99.3% of 271 | ≥80% support |
| Pfam | PF01434 | Peptidase_M41 — Peptidase family M41 | 252 / 304 | 82.9% | 92.0% of 274 | ≥80% support |
| Pfam | PF00004 | AAA | 250 / 304 | 82.2% | 91.2% of 274 | ≥80% support |
| GO | GO:0004176 Molecular Function | ATP-dependent peptidase activity | 271 / 304 | 89.1% | 100.0% of 271 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 271 / 304 | 89.1% | 100.0% of 271 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 269 / 304 | 88.5% | 99.3% of 271 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 254 / 304 | 83.6% | 93.7% of 271 | ≥80% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 250 / 304 | 82.2% | 92.3% of 271 | ≥80% support |
| Pfam | PF17862 | AAA_lid_3 — AAA+ lid domain | 238 / 304 | 78.3% | 86.9% of 274 | ≥50% support |
| GO | GO:0005743 Cellular Component | mitochondrial inner membrane | 207 / 304 | 68.1% | 76.4% of 271 | ≥50% support |
| GO | GO:0006515 Biological Process | protein quality control for misfolded or incompletely synthesized proteins | 207 / 304 | 68.1% | 76.4% of 271 | ≥50% support |
| GO | GO:0007005 Biological Process | mitochondrion organization | 207 / 304 | 68.1% | 76.4% of 271 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 185 / 304 | 60.9% | 68.3% of 271 | ≥50% support |
| KEGG | K08955 | YME1 — Peptidases and inhibitors | 185 / 304 | 60.9% | 80.4% of 230 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Galaxea fascicularis | gfas1.m1.21341.m1 | CAH3120989.1 | unnamed protein product [Porites lobata] | Q8LQJ8 ATP-dependent zinc metalloprotease FTSH 5, mitochondrial OS= | JBrowse |
| Galaxea fascicularis | gfas1.m1.22464.m1 | CAH3024216.1 | unnamed protein product [Porites evermanni] | Q96TA2 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX | JBrowse |
