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This orthogroup contains 275 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 275 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46130 | LAMGL DOMAIN-CONTAINING PROTEIN | 255 / 275 | 92.7% | 100.0% of 255 | ≥80% support |
| Pfam | PF00084 | Sushi | 230 / 275 | 83.6% | 92.7% of 248 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 255 / 275 | 92.7% | 100.0% of 255 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 255 / 275 | 92.7% | 100.0% of 255 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 255 / 275 | 92.7% | 100.0% of 255 | ≥80% support |
| GO | GO:0007166 Biological Process | cell surface receptor signaling pathway | 255 / 275 | 92.7% | 100.0% of 255 | ≥80% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 220 / 275 | 80.0% | 86.3% of 255 | ≥80% support |
| Pfam | PF05572 | Peptidase_M43 — Pregnancy-associated plasma protein-A | 217 / 275 | 78.9% | 87.5% of 248 | ≥50% support |
| Pfam | PF13385 | Laminin_G_3 — Concanavalin A-like lectin/glucanases superfamily | 214 / 275 | 77.8% | 86.3% of 248 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 165 / 275 | 60.0% | 64.7% of 255 | ≥50% support |
| KEGG | K07762 | PAPPA — Peptidases and inhibitors | 187 / 275 | 68.0% | 97.9% of 191 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Galaxea fascicularis | gfas1.m1.1537.m1 | XP_029182850.2 | pappalysin-1-like [Acropora millepora] | Q8R4K8 Pappalysin-1 OS=Mus musculus OX=10090 GN=Pappa PE=2 SV=2 | JBrowse |
