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This orthogroup contains 236 genes from 120 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 236 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 212 / 236 | 89.8% | 99.5% of 213 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 210 / 236 | 89.0% | 98.1% of 214 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 208 / 236 | 88.1% | 97.2% of 214 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 216 / 236 | 91.5% | 100.0% of 216 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 216 / 236 | 91.5% | 100.0% of 216 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 213 / 236 | 90.3% | 98.6% of 216 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 213 / 236 | 90.3% | 98.6% of 216 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 213 / 236 | 90.3% | 98.6% of 216 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 212 / 236 | 89.8% | 98.2% of 216 | ≥80% support |
| KEGG | K05312 | CHRNN — Ion channels | 144 / 236 | 61.0% | 98.6% of 146 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Galaxea fascicularis | gfas1.m1.13913.m1 | XP_022805137.1 | neuronal acetylcholine receptor subunit alpha-7-like isoform X1 [Stylophora pistillata] | P49582 Neuronal acetylcholine receptor subunit alpha-7 OS=Mus muscu | JBrowse |
