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This orthogroup contains 5,952 genes from 144 species (5,953 sequences — 1 extra sequences share a gene identifier with another member, so they are not counted twice). The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 5,952 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 5281 / 5,952 | 88.7% | 99.5% of 5,310 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 5226 / 5,952 | 87.8% | 95.8% of 5,453 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 5080 / 5,952 | 85.4% | 93.2% of 5,453 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 5523 / 5,952 | 92.8% | 100.0% of 5,523 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 5520 / 5,952 | 92.7% | 100.0% of 5,523 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 5302 / 5,952 | 89.1% | 96.0% of 5,523 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 5302 / 5,952 | 89.1% | 96.0% of 5,523 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 5302 / 5,952 | 89.1% | 96.0% of 5,523 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 5287 / 5,952 | 88.8% | 95.7% of 5,523 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 5282 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 5282 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 5281 / 5,952 | 88.7% | 95.6% of 5,523 | ≥80% support |
| GO | GO:0022848 Molecular Function | acetylcholine-gated monoatomic cation-selective channel activity | 3030 / 5,952 | 50.9% | 54.9% of 5,523 | ≥50% support |
| GO | GO:0045211 Cellular Component | postsynaptic membrane | 3021 / 5,952 | 50.8% | 54.7% of 5,523 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr01.360 | CAB4020368.1 | neuronal acetylcholine receptor subunit alpha-10-like [Paramuricea clavata] | P09482 Neuronal acetylcholine receptor subunit alpha-4 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr01.5652 | XP_028401556.1 | neuronal acetylcholine receptor subunit alpha-4-like isoform X2 [Dendronephthya gigantea] | P05376 Acetylcholine receptor subunit gamma OS=Xenopus laevis OX=83 | JBrowse |
| Hemicorallium imperiale | evm.model.Chr01.5653 | CAB3978504.1 | neuronal acetylcholine receptor subunit alpha-7-like [Paramuricea clavata] | P48180 Acetylcholine receptor subunit alpha-type acr-16 OS=Caenorha | JBrowse |
| Hemicorallium imperiale | evm.model.Chr02.598 | XP_028404611.1 | neuronal acetylcholine receptor subunit beta-3-like isoform X1 [Dendronephthya gigantea] | P20420 Neuronal acetylcholine receptor subunit alpha-5 OS=Rattus no | JBrowse |
| Hemicorallium imperiale | evm.model.Chr07.275 | CAB3988235.1 | neuronal acetylcholine receptor subunit alpha-10 [Paramuricea clavata] | P09480 Neuronal acetylcholine receptor subunit alpha-2 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr07.276 | XP_028392100.1 | neuronal acetylcholine receptor subunit alpha-7-like isoform X1 [Dendronephthya gigantea] | P09480 Neuronal acetylcholine receptor subunit alpha-2 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr07.280 | CAB3988233.1 | neuronal acetylcholine receptor subunit alpha-10 [Paramuricea clavata] | P49582 Neuronal acetylcholine receptor subunit alpha-7 OS=Mus muscu | JBrowse |
| Hemicorallium imperiale | evm.model.Chr10.658 | CAB3993613.1 | Glutathionyl-hydroquinone reductase [Paramuricea clavata] | Q494W8 CHRNA7-FAM7A fusion protein OS=Homo sapiens OX=9606 GN=CHRFA | JBrowse |
| Hemicorallium imperiale | evm.model.Chr10.660 | CAB3989191.1 | neuronal acetylcholine receptor subunit alpha-7-like, partial [Paramuricea clavata] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr10.661 | XP_028411576.1 | acetylcholine receptor subunit alpha-like isoform X1 [Dendronephthya gigantea] | P36544 Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapi | JBrowse |
| Hemicorallium imperiale | evm.model.Chr11.698 | XP_028406687.1 | neuronal acetylcholine receptor subunit beta-3-like [Dendronephthya gigantea] | P04757 Neuronal acetylcholine receptor subunit alpha-3 OS=Rattus no | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.368 | XP_028398914.1 | neuronal acetylcholine receptor subunit alpha-9-like [Dendronephthya gigantea] | P43144 Neuronal acetylcholine receptor subunit alpha-9 OS=Rattus no | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.781 | CAB4009546.1 | neuronal acetylcholine receptor subunit alpha-10-like [Paramuricea clavata] | P32297 Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapi | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.782 | CAB3998170.1 | neuronal acetylcholine receptor subunit alpha-10-like isoform X2 [Paramuricea clavata] | P49582 Neuronal acetylcholine receptor subunit alpha-7 OS=Mus muscu | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.783 | CAB3998169.1 | neuronal acetylcholine receptor subunit alpha-10-like [Paramuricea clavata] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.804 | XP_028399211.1 | acetylcholine receptor subunit alpha-type acr-16-like isoform X2 [Dendronephthya gigantea] | P48180 Acetylcholine receptor subunit alpha-type acr-16 OS=Caenorha | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.805 | XP_028399066.1 | neuronal acetylcholine receptor subunit alpha-2-like [Dendronephthya gigantea] | P09480 Neuronal acetylcholine receptor subunit alpha-2 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.806 | XP_028399066.1 | neuronal acetylcholine receptor subunit alpha-2-like [Dendronephthya gigantea] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
| Hemicorallium imperiale | evm.model.Chr12.807 | XP_028399064.1 | neuronal acetylcholine receptor subunit alpha-10-like isoform X2 [Dendronephthya gigantea] | P09478 Acetylcholine receptor subunit alpha-like 1 OS=Drosophila me | JBrowse |
| Hemicorallium imperiale | evm.model.Chr14.75 | XP_028410153.1 | neuronal acetylcholine receptor subunit alpha-7-like [Dendronephthya gigantea] | Q9JLB5 Neuronal acetylcholine receptor subunit alpha-10 OS=Rattus n | JBrowse |
