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This orthogroup contains 468 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 468 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10110 | SODIUM/HYDROGEN EXCHANGER | 383 / 468 | 81.8% | 99.7% of 384 | ≥80% support |
| Pfam | PF00999 | Na_H_Exchanger — Sodium/hydrogen exchanger family | 376 / 468 | 80.3% | 99.7% of 377 | ≥80% support |
| GO | GO:0015385 Molecular Function | sodium:proton antiporter activity | 402 / 468 | 85.9% | 99.8% of 403 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 402 / 468 | 85.9% | 99.8% of 403 | ≥80% support |
| GO | GO:0051453 Biological Process | regulation of intracellular pH | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:1902600 Biological Process | proton transmembrane transport | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0098719 Biological Process | sodium ion import across plasma membrane | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0071805 Biological Process | potassium ion transmembrane transport | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0055037 Cellular Component | recycling endosome | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0015386 Molecular Function | potassium:proton antiporter activity | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0006812 Biological Process | monoatomic cation transport | 383 / 468 | 81.8% | 95.0% of 403 | ≥80% support |
| GO | GO:0006885 Biological Process | regulation of pH | 381 / 468 | 81.4% | 94.5% of 403 | ≥80% support |
| GO | GO:0006814 Biological Process | sodium ion transport | 381 / 468 | 81.4% | 94.5% of 403 | ≥80% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 376 / 468 | 80.3% | 93.3% of 403 | ≥80% support |
| GO | GO:0015297 Molecular Function | antiporter activity | 376 / 468 | 80.3% | 93.3% of 403 | ≥80% support |
| KEGG | K12041 | SLC9A6_7, NHE6_7 — Transporters | 308 / 468 | 65.8% | 98.1% of 314 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr01.858 | XP_028402520.1 | sodium/hydrogen exchanger 7-like isoform X1 [Dendronephthya gigantea] | D3ZJ86 Sodium/hydrogen exchanger 6 OS=Rattus norvegicus OX=10116 GN | JBrowse |
| Hemicorallium imperiale | evm.model.Chr09.665 | CAB4022167.1 | sodium hydrogen exchanger 6-like isoform X2 [Paramuricea clavata] | Q96T83 Sodium/hydrogen exchanger 7 OS=Homo sapiens OX=9606 GN=SLC9A | JBrowse |
