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🧬 OG0002946

This orthogroup contains 317 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 79.5%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 317 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11347CYCLIC NUCLEOTIDE PHOSPHODIESTERASE252 / 31779.5%99.2%
of 254		≥50% support
PfamPF00233PDEase_I — 3'5'-cyclic nucleotide phosphodiesterase234 / 31773.8%90.4%
of 259		≥50% support
PfamPF01590GAF217 / 31768.5%83.8%
of 259		≥50% support
GOGO:0005634
Cellular Component		nucleus253 / 31779.8%96.6%
of 262		≥50% support
GOGO:0005829
Cellular Component		cytosol253 / 31779.8%96.6%
of 262		≥50% support
GOGO:0007165
Biological Process		signal transduction253 / 31779.8%96.6%
of 262		≥50% support
GOGO:0004114
Molecular Function		3',5'-cyclic-nucleotide phosphodiesterase activity253 / 31779.8%96.6%
of 262		≥50% support
GOGO:0010754
Biological Process		negative regulation of cGMP-mediated signaling252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0097060
Cellular Component		synaptic membrane252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0048471
Cellular Component		perinuclear region of cytoplasm252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0047555
Molecular Function		3',5'-cyclic-GMP phosphodiesterase activity252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0046069
Biological Process		cGMP catabolic process252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0043951
Biological Process		negative regulation of cAMP-mediated signaling252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0042803
Molecular Function		protein homodimerization activity252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0019934
Biological Process		cGMP-mediated signaling252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0019933
Biological Process		cAMP-mediated signaling252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0010821
Biological Process		regulation of mitochondrion organization252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0010628
Biological Process		positive regulation of gene expression252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0005759
Cellular Component		mitochondrial matrix252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0005743
Cellular Component		mitochondrial inner membrane252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0005741
Cellular Component		mitochondrial outer membrane252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0004118
Molecular Function		3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0004115
Molecular Function		3',5'-cyclic-AMP phosphodiesterase activity252 / 31779.5%96.2%
of 262		≥50% support
GOGO:0008081
Molecular Function		phosphoric diester hydrolase activity229 / 31772.2%87.4%
of 262		≥50% support
GOGO:0005515
Molecular Function		protein binding221 / 31769.7%84.4%
of 262		≥50% support
📊 Total members in OG0002946: 1 (filtered to HIMPE · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Hemicorallium imperialeevm.model.Chr01.696CAB3986027.1cGMP-dependent 3, 5 -cyclic phosphodiesterase [Paramuricea clavata]P14099
cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Bos taurus 		JBrowse
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