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This orthogroup contains 270 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 270 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22967 | SERINE/THREONINE PROTEIN KINASE | 175 / 270 | 64.8% | 76.1% of 230 | ≥50% support |
| Pfam | PF10409 | PTEN_C2 — C2 domain of PTEN tumour-suppressor protein | 190 / 270 | 70.4% | 85.6% of 222 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 185 / 270 | 68.5% | 83.3% of 222 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 199 / 270 | 73.7% | 86.5% of 230 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 185 / 270 | 68.5% | 80.4% of 230 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 185 / 270 | 68.5% | 80.4% of 230 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 185 / 270 | 68.5% | 80.4% of 230 | ≥50% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 176 / 270 | 65.2% | 76.5% of 230 | ≥50% support |
| GO | GO:0035612 Molecular Function | AP-2 adaptor complex binding | 171 / 270 | 63.3% | 74.4% of 230 | ≥50% support |
| GO | GO:0045747 Biological Process | positive regulation of Notch signaling pathway | 171 / 270 | 63.3% | 74.4% of 230 | ≥50% support |
| GO | GO:2000369 Biological Process | regulation of clathrin-dependent endocytosis | 171 / 270 | 63.3% | 74.4% of 230 | ≥50% support |
| KEGG | K08855 | GAK — Membrane trafficking | 157 / 270 | 58.2% | 96.3% of 163 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr02.97 | XP_028413049.1 | cyclin-G-associated kinase-like [Dendronephthya gigantea] | O14976 Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE | JBrowse |
