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This orthogroup contains 266 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 266 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00018 | SH3_1 — SH3 domain | 219 / 266 | 82.3% | 94.4% of 232 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 224 / 266 | 84.2% | 96.6% of 232 | ≥80% support |
| PANTHER | PTHR19969 | SH2-SH3 ADAPTOR PROTEIN-RELATED | 151 / 266 | 56.8% | 65.7% of 230 | ≥50% support |
| Pfam | PF00017 | SH2 | 168 / 266 | 63.2% | 72.4% of 232 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 154 / 266 | 57.9% | 66.4% of 232 | ≥50% support |
| GO | GO:0016477 Biological Process | cell migration | 152 / 266 | 57.1% | 65.5% of 232 | ≥50% support |
| GO | GO:0030971 Molecular Function | receptor tyrosine kinase binding | 151 / 266 | 56.8% | 65.1% of 232 | ≥50% support |
| GO | GO:0035591 Molecular Function | signaling adaptor activity | 151 / 266 | 56.8% | 65.1% of 232 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr01.6037 | XP_028409373.1 | cytoplasmic protein NCK2-like [Dendronephthya gigantea] | P16333 SH2/SH3 adapter protein NCK1 OS=Homo sapiens OX=9606 GN=NCK1 | JBrowse |
