Gene Family

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Member genes
258
Species
140
Sequences
258
Best annotation support
83.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 83.7% of the 258 members.

Support counts the member genes carrying the term. % of genes is that count over all 258 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR46097G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP216 / 25883.7%99.5%
of 217
≥80% support
GOGO:0005096
Molecular Function
GTPase activator activity216 / 25883.7%99.1%
of 218
≥80% support
GOGO:0007420
Biological Process
brain development216 / 25883.7%99.1%
of 218
≥80% support
GOGO:0008277
Biological Process
regulation of G protein-coupled receptor signaling pathway216 / 25883.7%99.1%
of 218
≥80% support
GOGO:0031267
Molecular Function
small GTPase binding216 / 25883.7%99.1%
of 218
≥80% support
GOGO:0032012
Biological Process
regulation of ARF protein signal transduction216 / 25883.7%99.1%
of 218
≥80% support
PfamPF12205GIT1_C — G protein-coupled receptor kinase-interacting protein 1 C term179 / 25869.4%81.7%
of 219
≥50% support
PfamPF08518GIT_SHD — Spa2 homology domain (SHD) of GIT173 / 25867.1%79.0%
of 219
≥50% support
PfamPF12796Ank_2 — Ankyrin repeats (3 copies)167 / 25864.7%76.3%
of 219
≥50% support
PfamPF01412ArfGap — Putative GTPase activating protein for Arf155 / 25860.1%70.8%
of 219
≥50% support
PfamPF16559GIT_CC — GIT coiled-coil Rho guanine nucleotide exchange factor133 / 25851.6%60.7%
of 219
≥50% support
GOGO:0005515
Molecular Function
protein binding170 / 25865.9%78.0%
of 218
≥50% support
KEGGK12487GIT2 — Membrane trafficking145 / 25856.2%95.4%
of 152
≥50% support
📊 Total members in OG0004420: 1 (filtered to HIMPE · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Hemicorallium imperialeevm.model.Chr04.1443XP_028400576.1ARF GTPase-activating protein GIT2-like isoform X2 [Dendronephthya gigantea]Q14161
ARF GTPase-activating protein GIT2 OS=Homo sapiens OX=9606 G
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