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This orthogroup contains 256 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 256 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13742 | RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0000785 Cellular Component | chromatin | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0000977 Molecular Function | RNA polymerase II transcription regulatory region sequence-specific DNA binding | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0005667 Cellular Component | transcription regulator complex | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0030154 Biological Process | cell differentiation | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0051726 Biological Process | regulation of cell cycle | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:2000134 Biological Process | negative regulation of G1/S transition of mitotic cell cycle | 224 / 256 | 87.5% | 100.0% of 224 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 208 / 256 | 81.3% | 92.9% of 224 | ≥80% support |
| Pfam | PF01857 | RB_B — Retinoblastoma-associated protein B domain | 194 / 256 | 75.8% | 86.2% of 225 | ≥50% support |
| Pfam | PF01858 | RB_A — Retinoblastoma-associated protein A domain | 189 / 256 | 73.8% | 84.0% of 225 | ≥50% support |
| Pfam | PF11934 | DUF3452 | 174 / 256 | 68.0% | 77.3% of 225 | ≥50% support |
| KEGG | K04681 | RBL1 — Transcription factors | 167 / 256 | 65.2% | 99.4% of 168 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr14.636 | XP_028391773.1 | LOW QUALITY PROTEIN: retinoblastoma-like protein 2 [Dendronephthya gigantea] | P28749 Retinoblastoma-like protein 1 OS=Homo sapiens OX=9606 GN=RBL | JBrowse |
