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This orthogroup contains 237 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 237 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14255 | CEREBLON | 168 / 237 | 70.9% | 92.3% of 182 | ≥50% support |
| Pfam | PF02190 | LON_substr_bdg — ATP-dependent protease La (LON) substrate-binding domain | 177 / 237 | 74.7% | 97.3% of 182 | ≥50% support |
| Pfam | PF03226 | Yippee-Mis18 — Yippee zinc-binding/DNA-binding /Mis18, centromere assembly | 160 / 237 | 67.5% | 87.9% of 182 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 168 / 237 | 70.9% | 100.0% of 168 | ≥50% support |
| GO | GO:0031464 Cellular Component | Cul4A-RING E3 ubiquitin ligase complex | 168 / 237 | 70.9% | 100.0% of 168 | ≥50% support |
| KEGG | K11793 | CRBN — Ubiquitin system | 170 / 237 | 71.7% | 100.0% of 170 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr01.5229 | CAB4017200.1 | cereblon-like isoform X3 [Paramuricea clavata] | Q68EH9 Protein cereblon OS=Danio rerio OX=7955 GN=crbn PE=1 SV=1 | JBrowse |
