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This orthogroup contains 237 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 237 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR15067 | E3 UBIQUITIN-PROTEIN LIGASE RNF8 | 181 / 237 | 76.4% | 95.3% of 190 | ≥50% support |
| Pfam | PF00498 | FHA | 182 / 237 | 76.8% | 92.9% of 196 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 184 / 237 | 77.6% | 86.4% of 213 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 183 / 237 | 77.2% | 85.9% of 213 | ≥50% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 182 / 237 | 76.8% | 85.5% of 213 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 182 / 237 | 76.8% | 85.5% of 213 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 182 / 237 | 76.8% | 85.5% of 213 | ≥50% support |
| GO | GO:0000151 Cellular Component | ubiquitin ligase complex | 181 / 237 | 76.4% | 85.0% of 213 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 181 / 237 | 76.4% | 85.0% of 213 | ≥50% support |
| GO | GO:0006302 Biological Process | double-strand break repair | 181 / 237 | 76.4% | 85.0% of 213 | ≥50% support |
| GO | GO:0035861 Cellular Component | site of double-strand break | 181 / 237 | 76.4% | 85.0% of 213 | ≥50% support |
| GO | GO:0042393 Molecular Function | histone binding | 181 / 237 | 76.4% | 85.0% of 213 | ≥50% support |
| GO | GO:0070936 Biological Process | protein K48-linked ubiquitination | 181 / 237 | 76.4% | 85.0% of 213 | ≥50% support |
| KEGG | K10667 | RNF8 — DNA repair and recombination proteins | 174 / 237 | 73.4% | 98.9% of 176 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr09.1452 | CAB3995002.1 | E3 ubiquitin- ligase RNF8-like [Paramuricea clavata] | O76064 E3 ubiquitin-protein ligase RNF8 OS=Homo sapiens OX=9606 GN= | JBrowse |
