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This orthogroup contains 224 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 224 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR15696 | SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 | 184 / 224 | 82.1% | 100.0% of 184 | ≥80% support |
| GO | GO:0000184 Biological Process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 184 / 224 | 82.1% | 98.9% of 186 | ≥80% support |
| GO | GO:0005697 Cellular Component | telomerase holoenzyme complex | 184 / 224 | 82.1% | 98.9% of 186 | ≥80% support |
| GO | GO:0042162 Molecular Function | telomeric DNA binding | 184 / 224 | 82.1% | 98.9% of 186 | ≥80% support |
| GO | GO:0070034 Molecular Function | telomerase RNA binding | 184 / 224 | 82.1% | 98.9% of 186 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 181 / 224 | 80.8% | 97.3% of 186 | ≥80% support |
| Pfam | PF10373 | EST1_DNA_bind — Est1 DNA/RNA binding domain | 169 / 224 | 75.5% | 91.4% of 185 | ≥50% support |
| Pfam | PF10374 | EST1 | 162 / 224 | 72.3% | 87.6% of 185 | ≥50% support |
| Pfam | PF13638 | PIN_4 — PIN domain | 156 / 224 | 69.6% | 84.3% of 185 | ≥50% support |
| KEGG | K11125 | SMG5, EST1B — DNA replication proteins | 146 / 224 | 65.2% | 100.0% of 146 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Hemicorallium imperiale | evm.model.Chr12.593 | XP_028406900.1 | protein SMG5-like [Dendronephthya gigantea] | Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 OS=Homo sapiens OX= | JBrowse |
