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This orthogroup contains 227 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 227 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11630 | DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0000727 Biological Process | double-strand break repair via break-induced replication | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0006268 Biological Process | DNA unwinding involved in DNA replication | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0006271 Biological Process | DNA strand elongation involved in DNA replication | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0017116 Molecular Function | single-stranded DNA helicase activity | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0032508 Biological Process | DNA duplex unwinding | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:0042555 Cellular Component | MCM complex | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| GO | GO:1902975 Biological Process | mitotic DNA replication initiation | 190 / 227 | 83.7% | 100.0% of 190 | ≥80% support |
| Pfam | PF17207 | MCM_OB — MCM OB domain | 173 / 227 | 76.2% | 88.7% of 195 | ≥50% support |
| Pfam | PF00493 | MCM | 169 / 227 | 74.5% | 86.7% of 195 | ≥50% support |
| Pfam | PF17855 | MCM_lid — MCM AAA-lid domain | 165 / 227 | 72.7% | 84.6% of 195 | ≥50% support |
| Pfam | PF14551 | MCM_N — MCM N-terminal domain | 161 / 227 | 70.9% | 82.6% of 195 | ≥50% support |
| GO | GO:0006270 Biological Process | DNA replication initiation | 172 / 227 | 75.8% | 90.5% of 190 | ≥50% support |
| GO | GO:0003678 Molecular Function | DNA helicase activity | 172 / 227 | 75.8% | 90.5% of 190 | ≥50% support |
| GO | GO:0006260 Biological Process | DNA replication | 161 / 227 | 70.9% | 84.7% of 190 | ≥50% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 139 / 227 | 61.2% | 73.2% of 190 | ≥50% support |
| KEGG | K02212 | MCM4, CDC54 — DNA replication proteins | 154 / 227 | 67.8% | 98.7% of 156 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Haliclystus octoradiatus | BRAKERHOCP00005015654.1 | XP_032230115.2 | DNA replication licensing factor mcm4-A [Nematostella vectensis] | P30664 DNA replication licensing factor mcm4-B OS=Xenopus laevis OX | JBrowse |
| Haliclystus octoradiatus | g18117.t1.1 | none | – | JBrowse |
