Gene Family

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Member genes
223
Species
144
Sequences
223
Best annotation support
81.6%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 81.6% of the 223 members.

Support counts the member genes carrying the term. % of genes is that count over all 223 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR47965ASPARTYL PROTEASE-RELATED182 / 22381.6%99.5%
of 183
≥80% support
PfamPF00026Asp190 / 22385.2%100.0%
of 190
≥80% support
GOGO:0004190
Molecular Function
aspartic-type endopeptidase activity187 / 22383.9%99.5%
of 188
≥80% support
GOGO:0006508
Biological Process
proteolysis187 / 22383.9%99.5%
of 188
≥80% support
GOGO:0016020
Cellular Component
membrane184 / 22382.5%97.9%
of 188
≥80% support
GOGO:0005768
Cellular Component
endosome182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0005802
Cellular Component
trans-Golgi network182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0005886
Cellular Component
plasma membrane182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0006509
Biological Process
membrane protein ectodomain proteolysis182 / 22381.6%96.8%
of 188
≥80% support
GOGO:0050435
Biological Process
amyloid-beta metabolic process182 / 22381.6%96.8%
of 188
≥80% support
KEGGK04521BACE1 — Peptidases and inhibitors158 / 22370.9%99.4%
of 159
≥50% support
📊 Total members in OG0006108: 2 (filtered to HOCTO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Haliclystus octoradiatusBRAKERHOCP00005020821.1XP_002166168.2beta-secretase 1 isoform X1 [Hydra vulgaris]P56819
Beta-secretase 1 OS=Rattus norvegicus OX=10116 GN=Bace1 PE=2
JBrowse
Haliclystus octoradiatusg9047.t1.1noneJBrowse
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