Gene Family

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Member genes
168
Species
128
Sequences
168
Best annotation support
88.1%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 88.1% of the 168 members.

Support counts the member genes carrying the term. % of genes is that count over all 168 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR12889GAMMA-SECRETASE SUBUNIT APH-1148 / 16888.1%99.3%
of 149
≥80% support
PfamPF06105Aph-1150 / 16889.3%100.0%
of 150
≥80% support
GOGO:0016020
Cellular Component
membrane150 / 16889.3%100.0%
of 150
≥80% support
GOGO:0016485
Biological Process
protein processing150 / 16889.3%100.0%
of 150
≥80% support
GOGO:0043085
Biological Process
positive regulation of catalytic activity150 / 16889.3%100.0%
of 150
≥80% support
GOGO:0005783
Cellular Component
endoplasmic reticulum148 / 16888.1%98.7%
of 150
≥80% support
GOGO:0016021
Cellular Component
membrane148 / 16888.1%98.7%
of 150
≥80% support
GOGO:0030674
Molecular Function
protein-macromolecule adaptor activity148 / 16888.1%98.7%
of 150
≥80% support
GOGO:0070765
Cellular Component
gamma-secretase complex148 / 16888.1%98.7%
of 150
≥80% support
KEGGK06172APH1 — Alzheimer disease141 / 16883.9%100.0%
of 141
≥80% support
📊 Total members in OG0008883: 2 (filtered to HOCTO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Haliclystus octoradiatusBRAKERHOCP00005002722.1KAJ7382712.1Notch receptor processing [Desmophyllum pertusum]Q8JHE9
Gamma-secretase subunit Aph-1b OS=Danio rerio OX=7955 GN=aph
JBrowse
Haliclystus octoradiatusg7190.t1.1noneJBrowse
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