Gene Family

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Member genes
1,386
Species
148
Sequences
1,386
Best annotation support
85.9%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 85.9% of the 1,386 members.

Support counts the member genes carrying the term. % of genes is that count over all 1,386 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR23255TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II1190 / 1,38685.9%100.0%
of 1,190
≥80% support
GOGO:0004675
Molecular Function
transmembrane receptor protein serine/threonine kinase activity1200 / 1,38686.6%99.9%
of 1,201
≥80% support
GOGO:0016020
Cellular Component
membrane1200 / 1,38686.6%99.9%
of 1,201
≥80% support
GOGO:0005524
Molecular Function
ATP binding1191 / 1,38685.9%99.2%
of 1,201
≥80% support
GOGO:0006468
Biological Process
protein phosphorylation1191 / 1,38685.9%99.2%
of 1,201
≥80% support
GOGO:0005886
Cellular Component
plasma membrane1190 / 1,38685.9%99.1%
of 1,201
≥80% support
GOGO:0007178
Biological Process
cell surface receptor protein serine/threonine kinase signaling pathway1190 / 1,38685.9%99.1%
of 1,201
≥80% support
GOGO:0004674
Molecular Function
protein serine/threonine kinase activity1180 / 1,38685.1%98.3%
of 1,201
≥80% support
GOGO:0043235
Cellular Component
receptor complex1180 / 1,38685.1%98.3%
of 1,201
≥80% support
GOGO:0071363
Biological Process
cellular response to growth factor stimulus1180 / 1,38685.1%98.3%
of 1,201
≥80% support
GOGO:0004672
Molecular Function
protein kinase activity1172 / 1,38684.6%97.6%
of 1,201
≥80% support
PfamPF07714PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase793 / 1,38657.2%68.1%
of 1,165
≥50% support
📊 Total members in OG0000505: 9 (filtered to HSYMB · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Hydractinia symbiolongicarpusHSymV2.0_g04.06106_t1XP_047138021.1activin receptor type-1C isoform X1 [Hydra vulgaris]P36897
TGF-beta receptor type-1 OS=Homo sapiens OX=9606 GN=TGFBR1 P
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g04.06561_t1XP_047138021.1activin receptor type-1C isoform X1 [Hydra vulgaris]P36897
TGF-beta receptor type-1 OS=Homo sapiens OX=9606 GN=TGFBR1 P
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g04.07025_t1XP_047139296.1activin receptor type-1 isoform X2 [Hydra vulgaris]Q04771
Activin receptor type-1 OS=Homo sapiens OX=9606 GN=ACVR1 PE=
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g04.07574_t1XP_047138021.1activin receptor type-1C isoform X1 [Hydra vulgaris]P80204
TGF-beta receptor type-1 OS=Rattus norvegicus OX=10116 GN=Tg
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g05.08685_t1XP_002154850.1activin receptor type-2A [Hydra vulgaris]P27039
Activin receptor type-2A OS=Xenopus laevis OX=8355 GN=acvr2a
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g06.10123_t1XP_002154850.1activin receptor type-2A [Hydra vulgaris]P27039
Activin receptor type-2A OS=Xenopus laevis OX=8355 GN=acvr2a
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g12.21081_t1XP_047137192.1bone morphogenetic protein receptor type-2 isoform X2 [Hydra vulgaris]Q13873
Bone morphogenetic protein receptor type-2 OS=Homo sapiens O
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g12.21856_t1XP_045113997.1activin receptor type-2A-like isoform X3 [Portunus trituberculatus]Q28043
Activin receptor type-2A OS=Bos taurus OX=9913 GN=ACVR2A PE=
JBrowse
Hydractinia symbiolongicarpusHSymV2.0_g15.25006_t1XP_002158603.3bone morphogenetic protein receptor type-1B [Hydra vulgaris]P36894
Bone morphogenetic protein receptor type-1A OS=Homo sapiens
JBrowse
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