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This orthogroup contains 4,302 genes from 145 species (4,305 sequences — 3 extra sequences share a gene identifier with another member, so they are not counted twice). The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 4,302 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24289 | STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE | 3634 / 4,302 | 84.5% | 91.1% of 3,989 | ≥80% support |
| Pfam | PF00067 | p450 | 3995 / 4,302 | 92.9% | 100.0% of 3,995 | ≥80% support |
| GO | GO:0004497 Molecular Function | monooxygenase activity | 4005 / 4,302 | 93.1% | 100.0% of 4,005 | ≥80% support |
| GO | GO:0005506 Molecular Function | iron ion binding | 4005 / 4,302 | 93.1% | 100.0% of 4,005 | ≥80% support |
| GO | GO:0016705 Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 4005 / 4,302 | 93.1% | 100.0% of 4,005 | ≥80% support |
| GO | GO:0020037 Molecular Function | heme binding | 4005 / 4,302 | 93.1% | 100.0% of 4,005 | ≥80% support |
| GO | GO:0004508 Molecular Function | steroid 17-alpha-monooxygenase activity | 3052 / 4,302 | 70.9% | 76.2% of 4,005 | ≥50% support |
| GO | GO:0042446 Biological Process | hormone biosynthetic process | 3052 / 4,302 | 70.9% | 76.2% of 4,005 | ≥50% support |
| GO | GO:0042448 Biological Process | progesterone metabolic process | 3052 / 4,302 | 70.9% | 76.2% of 4,005 | ≥50% support |
| GO | GO:0047442 Molecular Function | obsolete 17-alpha-hydroxyprogesterone aldolase activity | 3052 / 4,302 | 70.9% | 76.2% of 4,005 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_002569-T1 | KAJ7365848.1 | hypothetical protein OS493_002569 [Desmophyllum pertusum] | O73853 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Ictalurus puncta | JBrowse |
| Lophelia pertusa | OS493_004838-T1 | KAJ7374500.1 | hypothetical protein OS493_004838 [Desmophyllum pertusum] | Q92109 Cytochrome P450 1A3 OS=Oncorhynchus mykiss OX=8022 GN=cyp1a3 | JBrowse |
| Lophelia pertusa | OS493_004847-T1 | KAJ7374509.1 | hypothetical protein OS493_004847 [Desmophyllum pertusum] | Q92110 Cytochrome P450 1A1 OS=Oncorhynchus mykiss OX=8022 GN=cyp1a1 | JBrowse |
| Lophelia pertusa | OS493_004876-T1 | KAJ7374538.1 | hypothetical protein OS493_004876 [Desmophyllum pertusum] | P00184 Cytochrome P450 1A1 OS=Mus musculus OX=10090 GN=Cyp1a1 PE=1 | JBrowse |
| Lophelia pertusa | OS493_006407-T1 | KAJ7393433.1 | hypothetical protein OS493_006407 [Desmophyllum pertusum] | O73853 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Ictalurus puncta | JBrowse |
| Lophelia pertusa | OS493_015425-T1 | KAJ7372960.1 | hypothetical protein OS493_015425 [Desmophyllum pertusum] | P00186 Cytochrome P450 1A2 OS=Mus musculus OX=10090 GN=Cyp1a2 PE=1 | JBrowse |
| Lophelia pertusa | OS493_019175-T1 | KAJ7331590.1 | hypothetical protein OS493_019175 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_019176-T1 | KAJ7331591.1 | hypothetical protein OS493_019176 [Desmophyllum pertusum] | P12394 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Gallus gallus OX | JBrowse |
| Lophelia pertusa | OS493_019178-T1 | KAJ7331593.1 | hypothetical protein OS493_019178 [Desmophyllum pertusum] | Q92113 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Squalus acanthia | JBrowse |
| Lophelia pertusa | OS493_019179-T1 | KAJ7331594.1 | hypothetical protein OS493_019179 [Desmophyllum pertusum] | P00178 Cytochrome P450 2B4 OS=Oryctolagus cuniculus OX=9986 GN=CYP2 | JBrowse |
| Lophelia pertusa | OS493_019182-T1 | KAJ7331597.1 | hypothetical protein OS493_019182 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_019211-T1 | KAJ7331623.1 | hypothetical protein OS493_019211 [Desmophyllum pertusum] | O42457 Cytochrome P450 1A1 OS=Sparus aurata OX=8175 GN=cyp1a1 PE=2 | JBrowse |
| Lophelia pertusa | OS493_019212-T1 | KAJ7331624.1 | hypothetical protein OS493_019212 [Desmophyllum pertusum] | P12394 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Gallus gallus OX | JBrowse |
| Lophelia pertusa | OS493_019213-T1 | KAJ7331625.1 | hypothetical protein OS493_019213 [Desmophyllum pertusum] | P70085 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Oryzias latipes | JBrowse |
| Lophelia pertusa | OS493_019214-T1 | KAJ7331626.1 | hypothetical protein OS493_019214 [Desmophyllum pertusum] | O57525 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Rana dybowskii O | JBrowse |
| Lophelia pertusa | OS493_021978-T1 | KAJ7378675.1 | hypothetical protein OS493_021978 [Desmophyllum pertusum] | O73853 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Ictalurus puncta | JBrowse |
| Lophelia pertusa | OS493_024570-T1 | KAJ7390535.1 | hypothetical protein OS493_024570 [Desmophyllum pertusum] | Q6JZS3 Cytochrome P450 1A1 OS=Oryzias latipes OX=8090 GN=cyp1a1 PE= | JBrowse |
| Lophelia pertusa | OS493_026584-T1 | KAJ7327706.1 | hypothetical protein OS493_026584 [Desmophyllum pertusum] | Q92113 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Squalus acanthia | JBrowse |
| Lophelia pertusa | OS493_026585-T1 | KAJ7327707.1 | hypothetical protein OS493_026585 [Desmophyllum pertusum] | Q9GMC7 Steroid 17-alpha-hydroxylase/17,20 lyase OS=Bison bison OX=9 | JBrowse |
| Lophelia pertusa | OS493_034306-T1 | KAJ7370095.1 | hypothetical protein OS493_034306 [Desmophyllum pertusum] | Q92095 Cytochrome P450 1A1 OS=Opsanus tau OX=8068 GN=cyp1a1 PE=2 SV | JBrowse |
