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This orthogroup contains 752 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 752 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11972 | NADPH OXIDASE | 668 / 752 | 88.8% | 99.7% of 670 | ≥80% support |
| Pfam | PF08022 | FAD_binding_8 — FAD-binding domain | 602 / 752 | 80.1% | 92.8% of 649 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 670 / 752 | 89.1% | 100.0% of 670 | ≥80% support |
| GO | GO:0006952 Biological Process | defense response | 667 / 752 | 88.7% | 99.6% of 670 | ≥80% support |
| GO | GO:0016175 Molecular Function | superoxide-generating NAD(P)H oxidase activity | 667 / 752 | 88.7% | 99.6% of 670 | ≥80% support |
| GO | GO:0042554 Biological Process | superoxide anion generation | 667 / 752 | 88.7% | 99.6% of 670 | ≥80% support |
| GO | GO:0043020 Cellular Component | NADPH oxidase complex | 667 / 752 | 88.7% | 99.6% of 670 | ≥80% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 640 / 752 | 85.1% | 95.5% of 670 | ≥80% support |
| Pfam | PF08030 | NAD_binding_6 — Ferric reductase NAD binding domain | 597 / 752 | 79.4% | 92.0% of 649 | ≥50% support |
| Pfam | PF01794 | Ferric_reduct — Ferric reductase like transmembrane component | 504 / 752 | 67.0% | 77.7% of 649 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 561 / 752 | 74.6% | 83.7% of 670 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_009615-T1 | KAJ7363461.1 | hypothetical protein OS493_009615 [Desmophyllum pertusum] | P52649 NADPH oxidase 2 OS=Sus scrofa OX=9823 GN=CYBB PE=2 SV=3 | JBrowse |
| Lophelia pertusa | OS493_018398-T1 | KAJ7391355.1 | hypothetical protein OS493_018398 [Desmophyllum pertusum] | Q5R5C5 NADPH oxidase 4 OS=Pongo abelii OX=9601 GN=NOX4 PE=2 SV=2 | JBrowse |
| Lophelia pertusa | OS493_018399-T1 | KAJ7391356.1 | hypothetical protein OS493_018399 [Desmophyllum pertusum] | Q9JHI8 NADPH oxidase 4 OS=Mus musculus OX=10090 GN=Nox4 PE=1 SV=1 | JBrowse |
| Lophelia pertusa | OS493_019632-T1 | KAJ7378936.1 | hypothetical protein OS493_019632 [Desmophyllum pertusum] | P52649 NADPH oxidase 2 OS=Sus scrofa OX=9823 GN=CYBB PE=2 SV=3 | JBrowse |
| Lophelia pertusa | OS493_019633-T1 | KAJ7378937.1 | hypothetical protein OS493_019633 [Desmophyllum pertusum] | P04839 NADPH oxidase 2 OS=Homo sapiens OX=9606 GN=CYBB PE=1 SV=2 | JBrowse |
