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This orthogroup contains 675 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 675 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11850 | HOMEOBOX PROTEIN TRANSCRIPTION FACTORS | 572 / 675 | 84.7% | 99.8% of 573 | ≥80% support |
| Pfam | PF05920 | Homeobox_KN — Homeobox KN domain | 561 / 675 | 83.1% | 96.1% of 584 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 572 / 675 | 84.7% | 99.8% of 573 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 572 / 675 | 84.7% | 99.8% of 573 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 561 / 675 | 83.1% | 97.9% of 573 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 561 / 675 | 83.1% | 97.9% of 573 | ≥80% support |
| Pfam | PF16493 | Meis_PKNOX_N — N-terminal of Homeobox Meis and PKNOX1 | 500 / 675 | 74.1% | 85.6% of 584 | ≥50% support |
| GO | GO:0001228 Molecular Function | DNA-binding transcription activator activity, RNA polymerase II-specific | 397 / 675 | 58.8% | 69.3% of 573 | ≥50% support |
| GO | GO:0001654 Biological Process | eye development | 397 / 675 | 58.8% | 69.3% of 573 | ≥50% support |
| GO | GO:0008284 Biological Process | positive regulation of cell population proliferation | 397 / 675 | 58.8% | 69.3% of 573 | ≥50% support |
| GO | GO:0009880 Biological Process | embryonic pattern specification | 397 / 675 | 58.8% | 69.3% of 573 | ≥50% support |
| GO | GO:0009887 Biological Process | animal organ morphogenesis | 397 / 675 | 58.8% | 69.3% of 573 | ≥50% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 397 / 675 | 58.8% | 69.3% of 573 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_018253-T1 | KAJ7333081.1 | Homeobox protein pknox2 [Desmophyllum pertusum] | O70477 Homeobox protein PKNOX1 OS=Mus musculus OX=10090 GN=Pknox1 P | JBrowse |
| Lophelia pertusa | OS493_018254-T1 | KAJ7333082.1 | Homeobox protein pknox2 [Desmophyllum pertusum] | Q96KN3 Homeobox protein PKNOX2 OS=Homo sapiens OX=9606 GN=PKNOX2 PE | JBrowse |
| Lophelia pertusa | OS493_029189-T1 | KAJ7389767.1 | Homeobox protein Meis2 [Desmophyllum pertusum] | O00470 Homeobox protein Meis1 OS=Homo sapiens OX=9606 GN=MEIS1 PE=1 | JBrowse |