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This orthogroup contains 670 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 670 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10336 | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN | 540 / 670 | 80.6% | 99.6% of 542 | ≥80% support |
| GO | GO:0004435 Molecular Function | phosphatidylinositol phospholipase C activity | 540 / 670 | 80.6% | 99.3% of 544 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 540 / 670 | 80.6% | 99.3% of 544 | ≥80% support |
| GO | GO:0048015 Biological Process | phosphatidylinositol-mediated signaling | 540 / 670 | 80.6% | 99.3% of 544 | ≥80% support |
| GO | GO:0051209 Biological Process | release of sequestered calcium ion into cytosol | 540 / 670 | 80.6% | 99.3% of 544 | ≥80% support |
| Pfam | PF00388 | PI-PLC-X — Phosphatidylinositol-specific phospholipase C, X domain | 497 / 670 | 74.2% | 87.4% of 569 | ≥50% support |
| Pfam | PF00387 | PI-PLC-Y — Phosphatidylinositol-specific phospholipase C, Y domain | 467 / 670 | 69.7% | 82.1% of 569 | ≥50% support |
| Pfam | PF09279 | EF-hand_like — Phosphoinositide-specific phospholipase C, efhand-like | 439 / 670 | 65.5% | 77.2% of 569 | ≥50% support |
| Pfam | PF17787 | PH_14 — PH domain | 418 / 670 | 62.4% | 73.5% of 569 | ≥50% support |
| Pfam | PF06631 | DUF1154 | 373 / 670 | 55.7% | 65.6% of 569 | ≥50% support |
| GO | GO:0006629 Biological Process | lipid metabolic process | 530 / 670 | 79.1% | 97.4% of 544 | ≥50% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 530 / 670 | 79.1% | 97.4% of 544 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 479 / 670 | 71.5% | 88.1% of 544 | ≥50% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 403 / 670 | 60.2% | 74.1% of 544 | ≥50% support |
| KEGG | K05858 | PLCB — Membrane trafficking | 389 / 670 | 58.1% | 97.7% of 398 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_014241-T1 | KAJ7373093.1 | hypothetical protein OS493_014241 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_014242-T1 | KAJ7373094.1 | hypothetical protein OS493_014242 [Desmophyllum pertusum] | P10894 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase be | JBrowse |
| Lophelia pertusa | OS493_014248-T1 | KAJ7373100.1 | hypothetical protein OS493_014248 [Desmophyllum pertusum] | Q15147 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase be | JBrowse |
| Lophelia pertusa | OS493_014249-T1 | KAJ7373101.1 | hypothetical protein OS493_014249 [Desmophyllum pertusum] | Q15147 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase be | JBrowse |