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This orthogroup contains 592 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 592 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11889 | HEDGEHOG | 533 / 592 | 90.0% | 98.0% of 544 | ≥80% support |
| Pfam | PF01079 | Hint | 519 / 592 | 87.7% | 93.9% of 553 | ≥80% support |
| GO | GO:0007267 Biological Process | cell-cell signaling | 535 / 592 | 90.4% | 96.8% of 553 | ≥80% support |
| GO | GO:0016540 Biological Process | protein autoprocessing | 519 / 592 | 87.7% | 93.9% of 553 | ≥80% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 513 / 592 | 86.7% | 92.8% of 553 | ≥80% support |
| GO | GO:0010468 Biological Process | regulation of gene expression | 513 / 592 | 86.7% | 92.8% of 553 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 512 / 592 | 86.5% | 92.6% of 553 | ≥80% support |
| GO | GO:0001708 Biological Process | cell fate specification | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| GO | GO:0005113 Molecular Function | patched binding | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| GO | GO:0007224 Biological Process | smoothened signaling pathway | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| Pfam | PF01085 | HH_signal — Hedgehog amino-terminal signalling domain | 370 / 592 | 62.5% | 66.9% of 553 | ≥50% support |
| GO | GO:0016539 Biological Process | intein-mediated protein splicing | 389 / 592 | 65.7% | 70.3% of 553 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_020048-T1 | KAJ7331263.1 | hypothetical protein OS493_020048 [Desmophyllum pertusum] | Q91035 Sonic hedgehog protein OS=Gallus gallus OX=9031 GN=SHH PE=1 | JBrowse |
| Lophelia pertusa | OS493_026943-T1 | KAJ7371299.1 | hypothetical protein OS493_026943 [Desmophyllum pertusum] | Q14623 Indian hedgehog protein OS=Homo sapiens OX=9606 GN=IHH PE=1 | JBrowse |
| Lophelia pertusa | OS493_035505-T1 | KAJ7351780.1 | hypothetical protein OS493_035505 [Desmophyllum pertusum] | Q14623 Indian hedgehog protein OS=Homo sapiens OX=9606 GN=IHH PE=1 | JBrowse |
| Lophelia pertusa | OS493_037995-T1 | KAJ7369565.1 | hypothetical protein OS493_037995, partial [Desmophyllum pertusum] | Q91610 Desert hedgehog protein A OS=Xenopus laevis OX=8355 GN=dhh-a | JBrowse |
