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This orthogroup contains 441 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 441 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21257 | DELTA(14)-STEROL REDUCTASE | 381 / 441 | 86.4% | 100.0% of 381 | ≥80% support |
| Pfam | PF01222 | ERG4_ERG24 — Ergosterol biosynthesis ERG4/ERG24 family | 381 / 441 | 86.4% | 99.2% of 384 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 381 / 441 | 86.4% | 100.0% of 381 | ≥80% support |
| GO | GO:0016126 Biological Process | sterol biosynthetic process | 381 / 441 | 86.4% | 100.0% of 381 | ≥80% support |
| GO | GO:0016627 Molecular Function | oxidoreductase activity, acting on the CH-CH group of donors | 381 / 441 | 86.4% | 100.0% of 381 | ≥80% support |
| GO | GO:0016628 Molecular Function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | 381 / 441 | 86.4% | 100.0% of 381 | ≥80% support |
| GO | GO:0030176 Cellular Component | obsolete integral component of endoplasmic reticulum membrane | 381 / 441 | 86.4% | 100.0% of 381 | ≥80% support |
| GO | GO:0006695 Biological Process | cholesterol biosynthetic process | 377 / 441 | 85.5% | 99.0% of 381 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_007297-T1 | KAJ7374223.1 | hypothetical protein OS493_007297 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_007298-T1 | KAJ7374224.1 | hypothetical protein OS493_007298 [Desmophyllum pertusum] | O08984 Delta(14)-sterol reductase LBR OS=Rattus norvegicus OX=10116 | JBrowse |
| Lophelia pertusa | OS493_007299-T1 | KAJ7374225.1 | Delta(14)-sterol reductase [Desmophyllum pertusum] | Q8WMV1 Delta(14)-sterol reductase TM7SF2 OS=Bos taurus OX=9913 GN=T | JBrowse |
| Lophelia pertusa | OS493_017793-T1 | KAJ7379280.1 | 7-dehydrocholesterol reductase [Desmophyllum pertusum] | Q5E9J5 7-dehydrocholesterol reductase OS=Bos taurus OX=9913 GN=DHCR | JBrowse |
