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This orthogroup contains 414 genes from 108 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 414 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0015276 Molecular Function | ligand-gated monoatomic ion channel activity | 343 / 414 | 82.9% | 100.0% of 343 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 332 / 414 | 80.2% | 96.8% of 343 | ≥80% support |
| PANTHER | PTHR18966 | IONOTROPIC GLUTAMATE RECEPTOR | 326 / 414 | 78.7% | 100.0% of 326 | ≥50% support |
| Pfam | PF00060 | Lig_chan — Ligand-gated ion channel | 305 / 414 | 73.7% | 84.7% of 360 | ≥50% support |
| Pfam | PF10613 | Lig_chan-Glu_bd — Ligated ion channel L-glutamate- and glycine-binding site | 288 / 414 | 69.6% | 80.0% of 360 | ≥50% support |
| Pfam | PF00497 | SBP_bac_3 — Bacterial extracellular solute-binding proteins, family 3 | 261 / 414 | 63.0% | 72.5% of 360 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 325 / 414 | 78.5% | 94.8% of 343 | ≥50% support |
| GO | GO:0038023 Molecular Function | signaling receptor activity | 325 / 414 | 78.5% | 94.8% of 343 | ≥50% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 223 / 414 | 53.9% | 65.0% of 343 | ≥50% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 223 / 414 | 53.9% | 65.0% of 343 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_030930-T1 | KAJ7389545.1 | hypothetical protein OS493_030930 [Desmophyllum pertusum] | Q21415 Glutamate receptor ionotropic, kainate glr-3 OS=Caenorhabdit | JBrowse |
| Lophelia pertusa | OS493_030931-T1 | KAJ7389546.1 | hypothetical protein OS493_030931 [Desmophyllum pertusum] | O43424 Glutamate receptor ionotropic, delta-2 OS=Homo sapiens OX=96 | JBrowse |
| Lophelia pertusa | OS493_032941-T1 | KAJ7322758.1 | hypothetical protein OS493_032941 [Desmophyllum pertusum] | Q12879 Glutamate receptor ionotropic, NMDA 2A OS=Homo sapiens OX=96 | JBrowse |
| Lophelia pertusa | OS493_032949-T1 | KAJ7322766.1 | hypothetical protein OS493_032949 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_032950-T1 | KAJ7322767.1 | hypothetical protein OS493_032950 [Desmophyllum pertusum] | P48058 Glutamate receptor 4 OS=Homo sapiens OX=9606 GN=GRIA4 PE=1 S | JBrowse |
| Lophelia pertusa | OS493_036894-T1 | KAJ7351080.1 | hypothetical protein OS493_036894 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_036895-T1 | KAJ7351081.1 | hypothetical protein OS493_036895 [Desmophyllum pertusum] | A0A1L8F5J9 Glutamate receptor ionotropic, NMDA 1 OS=Xenopus laevis OX=8 | JBrowse |
