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This orthogroup contains 355 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 355 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11255 | DIACYLGLYCEROL KINASE | 292 / 355 | 82.3% | 92.1% of 317 | ≥80% support |
| GO | GO:0004143 Molecular Function | ATP-dependent diacylglycerol kinase activity | 292 / 355 | 82.3% | 95.4% of 306 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 292 / 355 | 82.3% | 95.4% of 306 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 289 / 355 | 81.4% | 94.4% of 306 | ≥80% support |
| GO | GO:0046339 Biological Process | diacylglycerol metabolic process | 289 / 355 | 81.4% | 94.4% of 306 | ≥80% support |
| GO | GO:0046834 Biological Process | lipid phosphorylation | 289 / 355 | 81.4% | 94.4% of 306 | ≥80% support |
| Pfam | PF00609 | DAGK_acc — Diacylglycerol kinase accessory domain | 265 / 355 | 74.7% | 83.6% of 317 | ≥50% support |
| Pfam | PF00781 | DAGK_cat — Diacylglycerol kinase catalytic domain | 261 / 355 | 73.5% | 82.3% of 317 | ≥50% support |
| Pfam | PF00130 | C1_1 — Phorbol esters/diacylglycerol binding domain (C1 domain) | 238 / 355 | 67.0% | 75.1% of 317 | ≥50% support |
| Pfam | PF00169 | PH | 231 / 355 | 65.1% | 72.9% of 317 | ≥50% support |
| Pfam | PF00536 | SAM_1 — SAM domain (Sterile alpha motif) | 195 / 355 | 54.9% | 61.5% of 317 | ≥50% support |
| GO | GO:0007205 Biological Process | obsolete protein kinase C-activating G protein-coupled receptor signaling pathway | 265 / 355 | 74.7% | 86.6% of 306 | ≥50% support |
| GO | GO:0016301 Molecular Function | kinase activity | 265 / 355 | 74.7% | 86.6% of 306 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 240 / 355 | 67.6% | 78.4% of 306 | ≥50% support |
| KEGG | K00901 | dgkA, DGK — Choline metabolism in cancer | 258 / 355 | 72.7% | 97.4% of 265 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_010445-T1 | KAJ7392786.1 | hypothetical protein OS493_010445 [Desmophyllum pertusum] | Q86XP1 Diacylglycerol kinase eta OS=Homo sapiens OX=9606 GN=DGKH PE | JBrowse |
| Lophelia pertusa | OS493_010446-T1 | KAJ7392787.1 | hypothetical protein OS493_010446 [Desmophyllum pertusum] | E9PUQ8 Diacylglycerol kinase delta OS=Mus musculus OX=10090 GN=Dgkd | JBrowse |
| Lophelia pertusa | OS493_010447-T1 | KAJ7392788.1 | hypothetical protein OS493_010447 [Desmophyllum pertusum] | Q64398 Diacylglycerol kinase eta OS=Mesocricetus auratus OX=10036 G | JBrowse |
| Lophelia pertusa | OS493_010448-T1 | KAJ7392789.1 | hypothetical protein OS493_010448 [Desmophyllum pertusum] | Q16760 Diacylglycerol kinase delta OS=Homo sapiens OX=9606 GN=DGKD | JBrowse |
