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This orthogroup contains 346 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 346 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF01485 | IBR | 297 / 346 | 85.8% | 96.1% of 309 | ≥80% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 297 / 346 | 85.8% | 95.8% of 310 | ≥80% support |
| GO | GO:0000151 Cellular Component | ubiquitin ligase complex | 294 / 346 | 85.0% | 94.8% of 310 | ≥80% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 294 / 346 | 85.0% | 94.8% of 310 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 279 / 346 | 80.6% | 90.0% of 310 | ≥80% support |
| PANTHER | PTHR11685 | RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING | 276 / 346 | 79.8% | 92.6% of 298 | ≥50% support |
| Pfam | PF05773 | RWD | 268 / 346 | 77.5% | 86.7% of 309 | ≥50% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 276 / 346 | 79.8% | 89.0% of 310 | ≥50% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 276 / 346 | 79.8% | 89.0% of 310 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 276 / 346 | 79.8% | 89.0% of 310 | ≥50% support |
| GO | GO:0031624 Molecular Function | ubiquitin conjugating enzyme binding | 276 / 346 | 79.8% | 89.0% of 310 | ≥50% support |
| GO | GO:0032436 Biological Process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | 276 / 346 | 79.8% | 89.0% of 310 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 276 / 346 | 79.8% | 89.0% of 310 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 269 / 346 | 77.8% | 86.8% of 310 | ≥50% support |
| KEGG | K11971 | RNF14, ARA54 — Ubiquitin system | 261 / 346 | 75.4% | 100.0% of 261 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_001807-T1 | KAJ7375075.1 | hypothetical protein OS493_001807 [Desmophyllum pertusum] | Q9UBS8 E3 ubiquitin-protein ligase RNF14 OS=Homo sapiens OX=9606 GN | JBrowse |
| Lophelia pertusa | OS493_023755-T1 | KAJ7357626.1 | E3 ubiquitin-protein ligase rnf14 [Desmophyllum pertusum] | F1RB95 E3 ubiquitin-protein ligase RNF14 OS=Danio rerio OX=7955 GN= | JBrowse |
