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This orthogroup contains 330 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 330 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10663 | GUANYL-NUCLEOTIDE EXCHANGE FACTOR | 270 / 330 | 81.8% | 98.9% of 273 | ≥80% support |
| Pfam | PF09324 | Sec7-like_HDS — Mon2/Sec7/BIG1-like, HDS | 229 / 330 | 69.4% | 80.1% of 286 | ≥50% support |
| Pfam | PF01369 | Sec7 | 225 / 330 | 68.2% | 78.7% of 286 | ≥50% support |
| Pfam | PF12783 | Sec7-like_HUS — Mon2/Sec7/BIG1-like, HUS domain | 222 / 330 | 67.3% | 77.6% of 286 | ≥50% support |
| Pfam | PF16213 | DCB — Mon2/Sec7/BIG1-like, dimerisation and cyclophilin-binding domain | 204 / 330 | 61.8% | 71.3% of 286 | ≥50% support |
| Pfam | PF20252 | BIG2_C — BIG2 C-terminal domain | 195 / 330 | 59.1% | 68.2% of 286 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 226 / 330 | 68.5% | 98.7% of 229 | ≥50% support |
| GO | GO:0032012 Biological Process | regulation of ARF protein signal transduction | 226 / 330 | 68.5% | 98.7% of 229 | ≥50% support |
| KEGG | K18442 | ARFGEF, BIG — Membrane trafficking | 199 / 330 | 60.3% | 97.6% of 204 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_009135-T1 | KAJ7373813.1 | Brefeldin A-inhibited guanine nucleotide-exchange protein 1 [Desmophyllum pertusum] | O46382 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 | JBrowse |
