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This orthogroup contains 323 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 323 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11472 | DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER | 293 / 323 | 90.7% | 100.0% of 293 | ≥80% support |
| GO | GO:0003678 Molecular Function | DNA helicase activity | 293 / 323 | 90.7% | 100.0% of 293 | ≥80% support |
| GO | GO:0003684 Molecular Function | damaged DNA binding | 293 / 323 | 90.7% | 100.0% of 293 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 293 / 323 | 90.7% | 100.0% of 293 | ≥80% support |
| GO | GO:0045951 Biological Process | positive regulation of mitotic recombination | 293 / 323 | 90.7% | 100.0% of 293 | ≥80% support |
| GO | GO:0006366 Biological Process | transcription by RNA polymerase II | 293 / 323 | 90.7% | 100.0% of 293 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 285 / 323 | 88.2% | 97.3% of 293 | ≥80% support |
| GO | GO:0016818 Molecular Function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 276 / 323 | 85.5% | 94.2% of 293 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 264 / 323 | 81.7% | 90.1% of 293 | ≥80% support |
| Pfam | PF06777 | HBB — Helical and beta-bridge domain | 240 / 323 | 74.3% | 86.6% of 277 | ≥50% support |
| Pfam | PF13307 | Helicase_C_2 — Helicase C-terminal domain | 239 / 323 | 74.0% | 86.3% of 277 | ≥50% support |
| Pfam | PF06733 | DEAD_2 | 235 / 323 | 72.8% | 84.8% of 277 | ≥50% support |
| GO | GO:0006289 Biological Process | nucleotide-excision repair | 248 / 323 | 76.8% | 84.6% of 293 | ≥50% support |
| GO | GO:0006139 Biological Process | nucleobase-containing compound metabolic process | 240 / 323 | 74.3% | 81.9% of 293 | ≥50% support |
| GO | GO:0004386 Molecular Function | helicase activity | 240 / 323 | 74.3% | 81.9% of 293 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 240 / 323 | 74.3% | 81.9% of 293 | ≥50% support |
| KEGG | K10844 | ERCC2, XPD — DNA repair and recombination proteins | 202 / 323 | 62.5% | 100.0% of 202 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_024926-T1 | KAJ7357415.1 | General transcription and DNA repair factor IIH helicase subunit XPD [Desmophyllum pertusum] | A6QLJ0 General transcription and DNA repair factor IIH helicase sub | JBrowse |
| Lophelia pertusa | OS493_024927-T1 | KAJ7357416.1 | General transcription and DNA repair factor IIH helicase subunit XPD [Desmophyllum pertusum] | A6QLJ0 General transcription and DNA repair factor IIH helicase sub | JBrowse |
| Lophelia pertusa | OS493_024928-T1 | KAJ7357417.1 | General transcription and DNA repair factor IIH helicase subunit XPD [Desmophyllum pertusum] | A6QLJ0 General transcription and DNA repair factor IIH helicase sub | JBrowse |
| Lophelia pertusa | OS493_024963-T1 | KAJ7357447.1 | General transcription and DNA repair factor IIH helicase subunit XPD [Desmophyllum pertusum] | A6QLJ0 General transcription and DNA repair factor IIH helicase sub | JBrowse |
