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This orthogroup contains 321 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 321 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0005524 Molecular Function | ATP binding | 259 / 321 | 80.7% | 100.0% of 259 | ≥80% support |
| GO | GO:0006298 Biological Process | mismatch repair | 258 / 321 | 80.4% | 99.6% of 259 | ≥80% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 258 / 321 | 80.4% | 99.6% of 259 | ≥80% support |
| PANTHER | PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | 253 / 321 | 78.8% | 98.8% of 256 | ≥50% support |
| Pfam | PF00488 | MutS_V — MutS domain V | 229 / 321 | 71.3% | 92.0% of 249 | ≥50% support |
| Pfam | PF05192 | MutS_III — MutS domain III | 200 / 321 | 62.3% | 80.3% of 249 | ≥50% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 253 / 321 | 78.8% | 97.7% of 259 | ≥50% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 253 / 321 | 78.8% | 97.7% of 259 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 240 / 321 | 74.8% | 92.7% of 259 | ≥50% support |
| GO | GO:0051026 Biological Process | chiasma assembly | 240 / 321 | 74.8% | 92.7% of 259 | ≥50% support |
| KEGG | K08741 | MSH5 — Chromosome and associated proteins | 187 / 321 | 58.3% | 90.3% of 207 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_015451-T1 | KAJ7372982.1 | mutS protein [Desmophyllum pertusum] | Q9QUM7 MutS protein homolog 5 OS=Mus musculus OX=10090 GN=Msh5 PE=1 | JBrowse |
