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This orthogroup contains 318 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 318 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR16171 | DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED | 268 / 318 | 84.3% | 98.5% of 272 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 268 / 318 | 84.3% | 98.5% of 272 | ≥80% support |
| GO | GO:0004520 Molecular Function | DNA endonuclease activity | 268 / 318 | 84.3% | 98.5% of 272 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 268 / 318 | 84.3% | 98.5% of 272 | ≥80% support |
| Pfam | PF00867 | XPG_I — XPG I-region | 209 / 318 | 65.7% | 85.0% of 246 | ≥50% support |
| Pfam | PF00752 | XPG_N — XPG N-terminal domain | 205 / 318 | 64.5% | 83.3% of 246 | ≥50% support |
| GO | GO:0004518 Molecular Function | nuclease activity | 245 / 318 | 77.0% | 90.1% of 272 | ≥50% support |
| GO | GO:0004519 Molecular Function | endonuclease activity | 226 / 318 | 71.1% | 83.1% of 272 | ≥50% support |
| GO | GO:0006289 Biological Process | nucleotide-excision repair | 226 / 318 | 71.1% | 83.1% of 272 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 207 / 318 | 65.1% | 76.1% of 272 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 207 / 318 | 65.1% | 76.1% of 272 | ≥50% support |
| GO | GO:0016788 Molecular Function | hydrolase activity, acting on ester bonds | 204 / 318 | 64.2% | 75.0% of 272 | ≥50% support |
| KEGG | K10846 | ERCC5, XPG, RAD2 — DNA repair and recombination proteins | 166 / 318 | 52.2% | 96.0% of 173 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_024140-T1 | KAJ7378193.1 | nucleotide-excision repair, DNA incision, 3'-to lesion [Desmophyllum pertusum] | P14629 DNA excision repair protein ERCC-5 homolog OS=Xenopus laevis | JBrowse |
| Lophelia pertusa | OS493_024141-T1 | KAJ7378194.1 | Helix-hairpin-helix class 2 (Pol1) motif [Desmophyllum pertusum] | P14629 DNA excision repair protein ERCC-5 homolog OS=Xenopus laevis | JBrowse |
| Lophelia pertusa | OS493_024143-T1 | KAJ7378196.1 | Ercc5p [Desmophyllum pertusum] | P14629 DNA excision repair protein ERCC-5 homolog OS=Xenopus laevis | JBrowse |
| Lophelia pertusa | OS493_024144-T1 | KAJ7378197.1 | nucleotide-excision repair, DNA incision, 3'-to lesion [Desmophyllum pertusum] | P35689 DNA excision repair protein ERCC-5 OS=Mus musculus OX=10090 | JBrowse |
