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This orthogroup contains 280 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 280 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24112 | LEUCINE-RICH REPEAT, ISOFORM F-RELATED | 212 / 280 | 75.7% | 98.6% of 215 | ≥50% support |
| Pfam | PF13516 | LRR_6 — Leucine Rich repeat | 199 / 280 | 71.1% | 89.2% of 223 | ≥50% support |
| Pfam | PF17888 | Carm_PH — Carmil pleckstrin homology domain | 172 / 280 | 61.4% | 77.1% of 223 | ≥50% support |
| Pfam | PF16000 | CARMIL_C — CARMIL C-terminus | 170 / 280 | 60.7% | 76.2% of 223 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 214 / 280 | 76.4% | 99.5% of 215 | ≥50% support |
| GO | GO:0016477 Biological Process | cell migration | 212 / 280 | 75.7% | 98.6% of 215 | ≥50% support |
| GO | GO:0030027 Cellular Component | lamellipodium | 212 / 280 | 75.7% | 98.6% of 215 | ≥50% support |
| GO | GO:0034315 Biological Process | regulation of Arp2/3 complex-mediated actin nucleation | 212 / 280 | 75.7% | 98.6% of 215 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 200 / 280 | 71.4% | 93.0% of 215 | ≥50% support |
| KEGG | K20493 | LRRC16, CARMIL — Membrane trafficking | 164 / 280 | 58.6% | 99.4% of 165 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_010092-T1 | KAJ7337235.1 | hypothetical protein OS493_010092 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_010093-T1 | KAJ7337236.1 | Leucine-rich repeat-containing protein 16A [Desmophyllum pertusum] | Q5VZK9 F-actin-uncapping protein LRRC16A OS=Homo sapiens OX=9606 GN | JBrowse |