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This orthogroup contains 278 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 278 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24131 | APOPTOSIS-STIMULATING OF P53 PROTEIN | 239 / 278 | 86.0% | 100.0% of 239 | ≥80% support |
| GO | GO:0002039 Molecular Function | p53 binding | 239 / 278 | 86.0% | 99.2% of 241 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 239 / 278 | 86.0% | 99.2% of 241 | ≥80% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 239 / 278 | 86.0% | 99.2% of 241 | ≥80% support |
| Pfam | PF12796 | Ank_2 — Ankyrin repeats (3 copies) | 214 / 278 | 77.0% | 91.5% of 234 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 208 / 278 | 74.8% | 88.9% of 234 | ≥50% support |
| Pfam | PF21712 | ASPP1-2_RA — Apoptosis-stimulating of p53 protein 1/2, RA domain | 150 / 278 | 54.0% | 64.1% of 234 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 218 / 278 | 78.4% | 90.5% of 241 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_022519-T1 | KAJ7378535.1 | hypothetical protein OS493_022519 [Desmophyllum pertusum] | Q13625 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=96 | JBrowse |
| Lophelia pertusa | OS493_022520-T1 | KAJ7378536.1 | hypothetical protein OS493_022520 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_022521-T1 | KAJ7378537.1 | hypothetical protein OS493_022521 [Desmophyllum pertusum] | Q8WUF5 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13 | JBrowse |
| Lophelia pertusa | OS493_022527-T1 | KAJ7378542.1 | hypothetical protein OS493_022527 [Desmophyllum pertusum] | Q13625 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=96 | JBrowse |
| Lophelia pertusa | OS493_022563-T1 | KAJ7378575.1 | hypothetical protein OS493_022563 [Desmophyllum pertusum] | Q13625 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=96 | JBrowse |
| Lophelia pertusa | OS493_022564-T1 | KAJ7378576.1 | hypothetical protein OS493_022564 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_022565-T1 | KAJ7378577.1 | hypothetical protein OS493_022565 [Desmophyllum pertusum] | Q8WUF5 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13 | JBrowse |