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This orthogroup contains 270 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 270 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24072 | RHO FAMILY GTPASE | 172 / 270 | 63.7% | 81.9% of 210 | ≥50% support |
| Pfam | PF08356 | EF_assoc_2 — EF hand associated | 208 / 270 | 77.0% | 92.9% of 224 | ≥50% support |
| Pfam | PF08355 | EF_assoc_1 — EF hand associated | 201 / 270 | 74.4% | 89.7% of 224 | ≥50% support |
| Pfam | PF00071 | Ras | 185 / 270 | 68.5% | 82.6% of 224 | ≥50% support |
| GO | GO:0003924 Molecular Function | GTPase activity | 196 / 270 | 72.6% | 92.0% of 213 | ≥50% support |
| GO | GO:0005525 Molecular Function | GTP binding | 196 / 270 | 72.6% | 92.0% of 213 | ≥50% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 187 / 270 | 69.3% | 87.8% of 213 | ≥50% support |
| GO | GO:0005741 Cellular Component | mitochondrial outer membrane | 179 / 270 | 66.3% | 84.0% of 213 | ≥50% support |
| GO | GO:0007005 Biological Process | mitochondrion organization | 179 / 270 | 66.3% | 84.0% of 213 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 172 / 270 | 63.7% | 80.8% of 213 | ≥50% support |
| GO | GO:0031307 Cellular Component | obsolete integral component of mitochondrial outer membrane | 139 / 270 | 51.5% | 65.3% of 213 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_010654-T1 | KAJ7386250.1 | Mitochondrial Rho GTPase 2 [Desmophyllum pertusum] | Q6NVC5 Mitochondrial Rho GTPase 1-A OS=Danio rerio OX=7955 GN=rhot1 | JBrowse |
| Lophelia pertusa | OS493_014426-T1 | KAJ7361785.1 | Mitochondrial Rho GTPase 2 [Desmophyllum pertusum] | Q5ZM83 Mitochondrial Rho GTPase 2 OS=Gallus gallus OX=9031 GN=RHOT2 | JBrowse |
