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This orthogroup contains 256 genes from 134 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 256 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12011 | ADHESION G-PROTEIN COUPLED RECEPTOR | 159 / 256 | 62.1% | 73.6% of 216 | ≥50% support |
| Pfam | PF00002 | 7tm_2 — 7 transmembrane receptor (Secretin family) | 191 / 256 | 74.6% | 87.6% of 218 | ≥50% support |
| Pfam | PF01825 | GPS | 184 / 256 | 71.9% | 84.4% of 218 | ≥50% support |
| Pfam | PF07679 | I-set | 164 / 256 | 64.1% | 75.2% of 218 | ≥50% support |
| Pfam | PF00084 | Sushi | 160 / 256 | 62.5% | 73.4% of 218 | ≥50% support |
| Pfam | PF16489 | GAIN | 159 / 256 | 62.1% | 72.9% of 218 | ≥50% support |
| Pfam | PF00754 | F5_F8_type_C — F5/8 type C domain | 156 / 256 | 60.9% | 71.6% of 218 | ≥50% support |
| Pfam | PF12947 | EGF_3 — EGF domain | 148 / 256 | 57.8% | 67.9% of 218 | ≥50% support |
| Pfam | PF13927 | Ig_3 — Immunoglobulin domain | 148 / 256 | 57.8% | 67.9% of 218 | ≥50% support |
| GO | GO:0004930 Molecular Function | G protein-coupled receptor activity | 193 / 256 | 75.4% | 89.8% of 215 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 192 / 256 | 75.0% | 89.3% of 215 | ≥50% support |
| GO | GO:0007186 Biological Process | G protein-coupled receptor signaling pathway | 192 / 256 | 75.0% | 89.3% of 215 | ≥50% support |
| GO | GO:0007166 Biological Process | cell surface receptor signaling pathway | 184 / 256 | 71.9% | 85.6% of 215 | ≥50% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 184 / 256 | 71.9% | 85.6% of 215 | ≥50% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 168 / 256 | 65.6% | 78.1% of 215 | ≥50% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 160 / 256 | 62.5% | 74.4% of 215 | ≥50% support |
| GO | GO:0007189 Biological Process | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 159 / 256 | 62.1% | 74.0% of 215 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_016153-T1 | KAJ7391863.1 | hypothetical protein OS493_016153 [Desmophyllum pertusum] | Q9P2N4 A disintegrin and metalloproteinase with thrombospondin moti | JBrowse |
| Lophelia pertusa | OS493_016154-T1 | KAJ7391864.1 | hypothetical protein OS493_016154 [Desmophyllum pertusum] | P48960 Adhesion G protein-coupled receptor E5 OS=Homo sapiens OX=96 | JBrowse |
