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This orthogroup contains 254 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 254 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14134 | E3 UBIQUITIN-PROTEIN LIGASE RAD18 | 206 / 254 | 81.1% | 100.0% of 206 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 206 / 254 | 81.1% | 99.0% of 208 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 206 / 254 | 81.1% | 99.0% of 208 | ≥80% support |
| GO | GO:0006301 Biological Process | postreplication repair | 206 / 254 | 81.1% | 99.0% of 208 | ≥80% support |
| GO | GO:0006513 Biological Process | protein monoubiquitination | 206 / 254 | 81.1% | 99.0% of 208 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 206 / 254 | 81.1% | 99.0% of 208 | ≥80% support |
| GO | GO:0097505 Cellular Component | Rad6-Rad18 complex | 206 / 254 | 81.1% | 99.0% of 208 | ≥80% support |
| Pfam | PF13923 | zf-C3HC4_2 — Zinc finger, C3HC4 type (RING finger) | 137 / 254 | 53.9% | 76.1% of 180 | ≥50% support |
| GO | GO:0006281 Biological Process | DNA repair | 174 / 254 | 68.5% | 83.7% of 208 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 173 / 254 | 68.1% | 83.2% of 208 | ≥50% support |
| KEGG | K10627 | RAD18 — DNA repair and recombination proteins | 155 / 254 | 61.0% | 99.4% of 156 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_034910-T1 | KAJ7376388.1 | E3 ubiquitin-protein ligase rad18 [Desmophyllum pertusum] | Q9NS91 E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN | JBrowse |
