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This orthogroup contains 243 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 243 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23358 | UNCHARACTERIZED | 211 / 243 | 86.8% | 98.1% of 215 | ≥80% support |
| Pfam | PF12851 | Tet_JBP — Oxygenase domain of the 2OGFeDO superfamily | 207 / 243 | 85.2% | 97.2% of 213 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 215 / 243 | 88.5% | 100.0% of 215 | ≥80% support |
| GO | GO:0006211 Biological Process | obsolete 5-methylcytosine catabolic process | 211 / 243 | 86.8% | 98.1% of 215 | ≥80% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 211 / 243 | 86.8% | 98.1% of 215 | ≥80% support |
| GO | GO:0070579 Molecular Function | 5-methylcytosine dioxygenase activity | 211 / 243 | 86.8% | 98.1% of 215 | ≥80% support |
| GO | GO:0080111 Biological Process | obsolete DNA demethylation | 211 / 243 | 86.8% | 98.1% of 215 | ≥80% support |
| Pfam | PF02008 | zf-CXXC — CXXC zinc finger domain | 146 / 243 | 60.1% | 68.5% of 213 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 161 / 243 | 66.3% | 74.9% of 215 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 160 / 243 | 65.8% | 74.4% of 215 | ≥50% support |
| KEGG | K24309 | TET2_3 — Chromosome and associated proteins | 136 / 243 | 56.0% | 97.8% of 139 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_016702-T1 | KAJ7372783.1 | Methylcytosine dioxygenase [Desmophyllum pertusum] | Q6N021 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=T | JBrowse |
