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This orthogroup contains 242 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 242 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21519 | PDZ DOMAIN-CONTAINING PROTEIN 8 | 214 / 242 | 88.4% | 100.0% of 214 | ≥80% support |
| GO | GO:0044233 Cellular Component | mitochondria-associated endoplasmic reticulum membrane contact site | 214 / 242 | 88.4% | 100.0% of 214 | ≥80% support |
| GO | GO:0051560 Biological Process | mitochondrial calcium ion homeostasis | 214 / 242 | 88.4% | 100.0% of 214 | ≥80% support |
| GO | GO:1990456 Biological Process | mitochondrion-endoplasmic reticulum membrane tethering | 214 / 242 | 88.4% | 100.0% of 214 | ≥80% support |
| Pfam | PF00168 | C2 | 173 / 242 | 71.5% | 87.8% of 197 | ≥50% support |
| Pfam | PF00130 | C1_1 — Phorbol esters/diacylglycerol binding domain (C1 domain) | 126 / 242 | 52.1% | 64.0% of 197 | ≥50% support |
| Pfam | PF17820 | PDZ_6 — PDZ domain | 124 / 242 | 51.2% | 62.9% of 197 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 177 / 242 | 73.1% | 82.7% of 214 | ≥50% support |
| GO | GO:0008289 Molecular Function | lipid binding | 173 / 242 | 71.5% | 80.8% of 214 | ≥50% support |
| KEGG | K24060 | PDZD8 — Domain-containing proteins not elsewhere classified | 141 / 242 | 58.3% | 98.6% of 143 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_021403-T1 | KAJ7371977.1 | PDZ domain-containing protein 8 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_021404-T1 | KAJ7371978.1 | PDZ domain-containing protein 8 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_021412-T1 | KAJ7371986.1 | PDZ domain-containing protein 8 [Desmophyllum pertusum] | – | JBrowse |
| Lophelia pertusa | OS493_021413-T1 | KAJ7371987.1 | PDZ domain-containing protein 8 [Desmophyllum pertusum] | Q8NEN9 PDZ domain-containing protein 8 OS=Homo sapiens OX=9606 GN=P | JBrowse |
| Lophelia pertusa | OS493_021416-T1 | KAJ7371990.1 | PDZ domain-containing protein 8 [Desmophyllum pertusum] | Q8NEN9 PDZ domain-containing protein 8 OS=Homo sapiens OX=9606 GN=P | JBrowse |
| Lophelia pertusa | OS493_021418-T1 | KAJ7371991.1 | PDZ domain-containing protein 8 [Desmophyllum pertusum] | – | JBrowse |